X-linked


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X-linked

 [eks´lingkt]
transmitted by genes on the X chromosome; see also X-linked gene.
The probabilities of male relatives being affected and female relatives being carriers of an X-linked recessive disorder. All the daughters of an affected male are obligate carriers. From Mueller and Young, 2001.

X-linked

(linkt),
Pertaining to genes borne on the X chromosome. Avoid confusing this word with sex-linked.

X-linked

(eks´linkt) transmitted by genes on the X chromosome; sex-linked.

X-linked

(ĕks′lĭngkt′)
adj.
Of, relating to, or characterized by genes located on the X chromosome.

X-linked

[eks′ lingkt]
pertaining to genes or to the characteristics or conditions they transmit that are carried on the X chromosome. Compare Y-linked. See also sex-linked disorder. X linkage, n.

X-linked

Sex linked Genetics adjective Referring to a mode of transmission in which a trait or gene is linked to the X chromosome and generally expressed only in males. See Gene, Mutation, Sex chromosome.

X-link·ed

(lingkt)
Pertaining to genes borne on the X chromosome. Commonly but erroneously used synonymously with sex-linked, which would also comprise Y-linked traits.

X-linked

Pertaining to genes, or to the effect of genes, situated on the X CHROMOSOME. X-linked disorders are those caused by mutated genes on the X chromosome. They include AGAMMAGLOBULINAEMIA, ALBINISM, ALPORT SYNDROME, Charcot-Marie-Tooth peroneal muscular atrophy, COLOUR BLINDNESS, DIABETES INSIPIDUS, ectodermal dysplasia, glucose-6-phosphate dehydrogenase deficiency, FABRY DISEASE, glycogen storage disease VIII, gonadal dysgenesis, HAEMOPHILIA A, one form of HYDROCEPHALUS, HYPOPHOSPHATAEMIA, ICHTHYOSIS, TURNER'S SYNDROME, one form of mental retardation, Becker and Duchesse MUSCULAR DYSTROPHY, one form of RETINITIS PIGMENTOSA and the TESTICULAR FEMINIZATION SYNDROME.

X-linked

Located on the X chromosome, one of the sex chromosomes. X-linked genes follow a characteristic pattern of inheritance from one generation to the next.

X-link·ed

(lingkt)
Pertaining to genes borne on the X chromosome.

X-linked

traits transmitted by genes on the X chromosome; sex-linked; the categories are X-linked dominant, X-linked recessive.

X-linked agammaglobinemia
see Bruton's agammaglobulinemia.
X-linked trait
sex-linked, e.g. coat color in cats, hemophilia.
References in periodicals archive ?
However, based on pedigree analysis, X-linked recessive inheritance is most likely, which is similar to the recent report of clustering in a family.
As described earlier, with reference to genotype on a single locus, there are twenty five different parent unions possible in nuclear pedigrees, six for each of autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive (6+6+6+6 = 24) and one for Y-linked inheritance pattern.
X-linked juvenile retinoschisis: clinical diagnosis, genetic analysis, and molecular mechanisms.
818_819insGGGCT mutation had an X-linked family history.
Clinical and mutational features of X-linked agammaglobulinemia in Mexico.
A recurrent missense mutation in the KAL gene in patients with X-linked kallmann's syndrome.
This suggests that the mutation was inherited from the mother and not the father The sequencing of UBQLN2-S3401 in this case indicated the presence of an X-linked ALS/FTD with incomplete penetrance in this family (Figure l).
G6PD deficiency is an X-linked congenital enzymopathy4 being present in more than 400 million people worldwide which increases the vulnerability of erythrocytes to oxidative stress.
In 2011, a 19-year-old white man from Ohio, USA, who had X-linked CGD was examined for right neck swelling and tenderness (2 weeks' duration), a yellow ulcerated lesion on the right side of the hard palate, and an enlarged right tonsil with copious exudate.
X-linked AHC is caused predominantly by point mutations in the NR0B1 (DAX1) gene; however it can also result from its partial or complete deletion.
Bazex-Dupre-Christol (BDC) syndrome is an X-linked dominant multiple basal cell carcinoma (BCC) syndrome, clinically characterized by follicular atrophoderma, multiple milia, hypotrichosis and multiple basal cell carcinomas.