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acronymic syndrome of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness, of uncertain cause.
Synonym(s): Wolfram syndrome
Etymology: D.J. Wolfram, American physician, 20th century
an autosomal-recessive syndrome, first evident in childhood, consisting of diabetes mellitus, diabetes insipidus, optic atrophy, and neural deafness. Also called DIDMOAD syndrome.
Wolf·ram syn·drome(wulf'răm sin'drōm)
A disorder consisting of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness; the genetic abnormality is located on chromosome 4p; autosomal recessive inheritance.
Wolfram,Donald J., U.S. physician, 1910–.
Wolfram syndrome - autosomal recessive disorder characterized by juvenile diabetes mellitus and optic atrophy. The acronym DIDMOAD is used to describe the syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and deafness).