Wilms tumor


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Wilms tu·mor

(wilmz), Avoid the misspellings Wilm and Wilm's.
a malignant renal tumor of young children, composed of small spindle cells and various other types of tissue, including tubules and, in some cases, structures resembling fetal glomeruli and striated muscle and cartilage; often inherited as an autosomal dominant trait [MIM*194070, *194080, *194090].
Synonym(s): nephroblastoma

Wilms tu·mor

(vilmz tū'mŏr)
A malignant renal tumor of young children, composed of small spindle cells and various other types of tissue, including tubules and, in some cases, structures resembling fetal glomeruli, and striated muscle and cartilage. Often inherited as an autosomal dominant trait.
Synonym(s): nephroblastoma.

Wilms tumor

(vilmz)
[Max Wilms, Ger. surgeon, 1867–1918]
A rapidly developing tumor of the kidney that usually occurs in children. It is the most common renal tumor of childhood. It is associated with chromosomal deletions, esp. from chromosomes 11 and 16. In the past, the mortality from this type of cancer was extremely high; however, newer approaches to therapy have been very effective in controlling the tumor in about 90% of patients.
Synonym: embryonal carcinosarcoma; nephroblastoma

Wilms,

Max, German surgeon, 1867-1918.
Wilms syndrome - Synonym(s): Wilms tumor
Wilms tumor - a malignant renal tumor of young children. Synonym(s): adenomyosarcoma; embryoma of the kidney; nephroblastoma; Wilms syndrome
References in periodicals archive ?
Among the neoplasms, Wilms tumor is the commonest renal tumor of childhood representing approximately 10% of all childhood malignancies that arises from embryological precursors of renal parenchyma (metanephros) with a peak incidence between 3-4 years; it is uncommon above the age of 5 and is rare in neonates1.
Neuberg et al., "Characteristics and outcome of children with Beckwith-Wiedemann syndrome and Wilms' tumor: a report from the National Wilms Tumor Study Group," Journal of Clinical Oncology, vol.
Immunohistochemistry of primary malignant neuroepithelial tumors of the kidney: a potential source of confusion?: a study of 30 cases from the National Wilms Tumor Study Pathology Center.
Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene 2002;21:6694-702.
Detection of preoperative Wilms tumor rupture with CT: A report from the Children's Oncology Group.
Eventually, those kidneys took on the appearance of Wilms tumors.
Jadresic L, Leake J, Gordon I: Clinicopathologic review of twelve children with nephropathy, Wilms tumor, and genital abnormalities (Drash syndrome).
BACKGROUND: Previous epidemiologic studies have suggested that exposure to pesticides in utero and during early childhood may increase the risk for development of childhood cancer, including Wilms tumor, a childhood kidney tumor.
Sarah, of Scholes, suffers from a Wilms tumor, which is a form of childhood kidney cancer.
She had undergone left nephrectomy and radiation therapy at 4 years of age for Wilms tumor. There was no evidence of tumor recurrence, and she had normal renal function.
7 Drummond IA, Madden SL, Rohwer-Nutter P, Bell GI, Sukhatme VP, Rauscher FJ: Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1.