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The researchers used the whole genome shotgun sequencing approach, which essentially breaks up the genome into smaller, more workable segments for analysis and then pieces them together.
Assuming ultrahigh-throughput sequencing accuracy improves, there would still be a need for a minimal coverage to achieve completeness in the likely scenario that whole genome shotgun sequencing will be the method used.
In conjunction with the significant preliminary mapping and sequencing progress contributed by Jean Weissenbach's group at GenoScope in Envry, France, Agencourt provided another 2 million double-ended whole genome shotgun sequencing reads required to unveil the mystery of this genome.
Myers, a group leader at Janelia Farm, joins Helicos' advisory board with extensive experience in genomic bioinformatics, including the initial proposal and eventual accomplishment of the whole genome shotgun sequencing of the Drosophila, Human, Mouse, and Anopheles genomes.
With genome centers' increasing reliance on whole genome shotgun sequencing, fosmid end sequencing has become a necessity for every genome project.
Through Celera's whole genome shotgun sequencing of five individuals, the group has identified approximately 30,000 genes and amassed a database of more than three million candidate SNPs.
This is another validation of Celera's Whole Genome Shotgun sequencing and assembly strategy.
Venter, who has a background as a Vietnam War medic and later a wunderkind biochemist, gives NOVA a tour of his operation at Celera Genomics ("celera" means speed in Latin), which uses a fully automated technique called whole genome shotgun sequencing to accelerate the mapping process.
We completed the sequence and assembly of both the fruit fly and human genomes in time frames previously thought impossible, demonstrating the viability of the whole genome shotgun sequencing approach.
Third, the Drosophila Genome Database provides the complete sequence of the Drosophila melanogaster genome generated by Celera's whole genome shotgun sequencing strategy.
Second, the Drosophila Genome Database and Drosophila Gene Index provide the complete sequence of the Drosophila melanogaster genome generated by Celera's whole genome shotgun sequencing strategy.
Third, the Drosophila Genome Database provides the complete sequence of the Drosophila melanogaster genome sequence generated by Celera's whole genome shotgun sequencing strategy.