West African sleeping sickness

Gam·bi·an try·pan·o·so·mi·a·sis

a chronic disease of humans caused by Trypanosoma brucei gambiense in northern and sub-Saharan Africa from Senegal east to Sudan and Uganda; characterized by splenomegaly, drowsiness, an uncontrollable urge to sleep, and the development of psychotic changes; basal ganglia and cerebellar involvement commonly lead to chorea and athetosis; the terminal phase of the disease is characterized by wasting, anorexia, and emaciation that gradually leads to coma and death, usually from intercurrent infection.

West African sleeping sickness

References in periodicals archive ?
Morphologically, both are indistinguishable but differ in clinical course and geographic distribution, East African being more rapidly progressive disease as compared to West African sleeping sickness.
While West African sleeping sickness is slowly progressive disease, CNS involvement occurs in 1-2 years and death usually occurs within 3 years but may be prolonged for up to 6-7 years.

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