Werner-His disease


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A louse-borne, rickettsial—R Quintana—infection
Locations Mexico, N. Africa, E Europe, etc
Transmission Direct contact—rubbing infected lousy feces into abraded skin or conjunctivae Clinical

Werner-His disease

His-Werner disease, trench fever, Wolhynia fever A louse-borne disease caused by Rochalimaea quintana, a rickettsia that multiplies in the gut of body lice Epidemiology Mexico, northern Africa, eastern Europe, etc; transmission by rubbing infected louse feces into abraded–scuffed skin or conjunctiva Clinical Abrupt onset of high fever, headache, back and leg pain, fleeting rash; recovery takes a month or more; relapses common Management If Sx are systemic or prolonged, ciprofloxacine, doxycycline
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