Weber-Christian syndrome


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Weber-Christian syndrome

A rare idiopathic condition that primarily affects adult females; it is a diagnosis of exclusion.
 
Clinical findings
Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia), hepatosplenomegaly, abdominal pain and episcleritis.
 
Lab
Nonspecific; leukopenia, increased ESR, rheumatoid factor, cryoglobulinemia.
 
DiffDx
Erythema induratum, sarcoidosis, post-injection fat necrosis.

Management
Symptomatic relief with corticosteroids, chloroquine, phenylbutazone.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Weber-Christian syndrome

Relapsing nodular nonsuppurative panniculitis A rare idiopathic condition, which primarily affects adult ♀ Clinical Crops of subcutaneous nodules on the thighs, abdomen, arms, and breasts, accompanied by fever, local inflammation, rheumatic complaints–arthritis, arthralgia, myalgia, hepatosplenomegaly, abdominal pain, & episcleritis Lab Nonspecific; leukopenia, ↑ ESR, rheumatoid factor, cryoglobulinemia DiffDx Erythema induratum, sarcoidosis, postinjection fat necrosis Management Symptomatic relief with corticosteroids, chloroquine, phenylbutazone. See Panniculitis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.