CDKN1C

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CDKN1C

A gene on chromosome 11p15.5 that encodes a strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation.

Molecular pathology
CDKN1C mutation is implicated in sporadic cancers and Beckwith-Wiedemann syndrome, suggesting a role in tumour suppression.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Conclusions can be drawn only about a level one versus level two comparison with regard to the breakout of WBS level two into the basic airframe and other air vehicle components.
(*3) WBs were performed with both the licensed test kit available in the United States and with laboratories' own WB test reagents using viral antigen purchased from commercial sources.
Posttreatment WBS with SPECT/CT showed physiologic uptake in the area of the thyroid bed as well as focal accumulation of radioiodine in the abdomen likely corresponding to a granuloma in the liver and a simple cyst in the left kidney as demonstrated by a follow-up sonogram.
Before becoming Dean of WBS in early 2010, Professor Taylor was a Managing Director at BlackRock, the world's largest asset manager, where he ran the European arm of a large global macro investment fund.
T&R's legal structure aims to emulate the WBS framework, but we view it as weaker than the UK's administration receivership framework utilised in WBS.
Planar I-131 WBS was performed in both anterior and posterior projections using dual-head gamma-camera (Infinia Hawkeye 4[R], GE Healthcare) with high-energy, parallel-hole collimators.
Given the pitfalls associated with utilization of Tg and WBS for follow-up of DTC, additional modalities need to be considered to assess recurrence.
'Warner-Bratzler' Shear (WBS) test determined the work of shearing (N s), that is, the work needed to move the blade through the sample, estimated with a Warner-Bratzler blade attached to the same texture analyser.
This case report presents the long-term orthodontic follow-up and treatment of a female patient with WBS and an isolated cleft palate from the age of 5 to 24 years.
Williams-Beuren Syndrome (WBS) was first described by Williams and Beuren independently in 1961 [4, 5].
The WBS images of patients having undetectable serum Tg levels but positive WBS results were reviewed by 2 experienced nuclear medicine physicians.
Warner-Bratzler shear force (WBS) is the most widely used estimator of sensory meat tenderness; it is in fact the only method used for raw meat and is suitable for commercial application (Culioli, 1995; Shackelford et al., 1995; 1999; Wheeler et al., 1997; de Huidobro et al., 2005).