Farlex Partner Medical Dictionary © Farlex 2012
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X4 is also planning to commence clinical trials of mavorixafor in Severe Congenital Neutropenia (SCN) and Waldenstrom's macroglobulinemia (WM) in 2019.
Calquence is being developed for the treatment of multiple B-cell blood cancers including CLL, MCL, diffuse large B-cell lymphoma, Waldenstrom macroglobulinemia, follicular lymphoma, and multiple myeloma and other hematologic malignancies.
This will likely prove definitive in the head-to-head Phase III trials to read out later in the year in Waldenstrom macroglobulinemia, Van Buren tells investors in a research note titled "The BeiGene Global Portfolio Development Strategy Remains On Track." Further, the analyst finds the combo's activity in chronic lymphocytic leukemia/small lymphocytic lymphoma and Hodgkin's lymphoma "promising."
Summary: Waldenstrom macroglobulinemia is a rare cancer and is characterized by high level of immunoglobulin M (IgM) in the serum, which leads to increased serum viscosity, and presence of a lymphoplasmacytic infiltrate in the bone marrow.
The second is for use of ibrutinib and rituximab for the treatment of earlier untreated and relapsed/refractory adults with Waldenstrom's macroglobulinemia.
Disease prevention company The Janssen Pharmaceutical Companies of Johnson & Johnson Tuesday received the US Food and Drug Administration (FDA) approval for IMBRUVICA (ibrutinib) in combination with rituximab for the treatment of Waldenstrom's macroglobulinemia (WM), a rare blood cancer.
The 52-year-old former Diamonds star and assistant manager, affectionately known as "Lumber" by the Broomfield fans, has been diagnosed with a form of cancer known as waldenstrom macroglobulinemia.
When variables such as general health, socio-economic status, education and parity are controlled for, as they are in hospital-based or cohort studies, the risk of stillbirth for women of AMA is smaller (Flenady et al., 2011; Waldenstrom, Cnattingius, Norman, & Schytt, 2015).
On day 3 after his Mohs procedure, one 73-year-old man taking ibrutinib for Waldenstrom macroglobulinemia developed extensive bilateral periorbital ecchymosis that extended down to his upper chest.
The prognosis of Schnitzler's syndrome is linked to the evolution of the lymphoproliferative disorder (15-20%), whether lymphomas, including lymphoplasmacytic lymphoma, Richter-type lymphoma, marginal zone lymphoma, myeloma or Waldenstrom's disease.