Waldenström's macroglobulinaemia

Waldenström's macroglobulinaemia

A rare disease of elderly people in which a MONOCLONAL immunoglobulin, IgM, is present in excessive quantities in the blood. This is caused by a cancerous overgrowth of B LYMPHOCYTES in the bone marrow. The condition progresses to immune deficiency. Treatment is by PLASMAPHERESIS and the use of the drug CHLORAMBUCIL. (Jan Waldenström, Swedish physician, b. 1906).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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