Wada test


Also found in: Wikipedia.

Wa·da test

(wah-dah),
unilateral internal carotid injection of amobarbital to determine the laterality of speech; injection on the dominant side causes transient aphasia or mutism; used prior to surgical treatment of epilepsy.
A test carried out under the influence of Amytal, a sedative, to localise speech function before a temporal lobectomy in patients with medically refractory epilepsy. Amytal® interview was later used to evaluate memory which, by causing full relaxation with minimal sedation, may elicit information from a person who is voluntarily ‘guarding’ against its revelation

Wada test

Neurosurgery A test used to determine which side of the brain contains higher language functions. See Left brain.

Wada,

John A., Japanese-Canadian neurosurgeon, 1924–.
Wada test - unilateral internal carotid injection of amobarbital to determine the laterality of speech.
References in periodicals archive ?
The 16 patients in the surgery group with left HS except for one case of hippocampal gliosis (MRI) and 5 cases of left-handed children all underwent Wada test before the surgery by the carotid injection of 2-4 mg clonazepam.
Wada test: 39 patients passed the Wada test at one time (=5/6) and three cases failed (=4/6) demonstrating that the bilateral temporal lobes were involved in memory and language processes.
The Wada test, or intra-carotid amytal procedure (IAP), has been considered the gold standard for lateralising language.
Findings from threshold-independent measures have been shown to correlate most strongly with other lateralisation techniques, such as the Wada test.
By establishing a correlation between cerebral dominance and sidedness of cell phone use, it may be possible to develop a less-invasive, lower-cost option to establish the side of the brain where speech and language occurs rather than the Wada test, a procedure that injects an anesthetic into the carotid artery to put part of the brain to sleep in order to map activity.
Because fMRI is based on a noninvasive, endogenous signal, it has the potential to replace the invasive Wada test (also known as the intracarotid amytal test), which is the current gold standard in language and memory lateralization.
The Wada test produces information about both language and memory function.
Investigators at the Montreal Neurologic Institute became concerned that several patients developed severe memory loss after undergoing temporal lobe resections and the Wada test was revised to include a battery of memory and cognitive tests to screen patients scheduled for surgical resection to prevent postoperative amnesia.
The doping saga of Indian weightlifting, which has so far seen five lifters test positive in the WADA tests, has now reached dangerous proportions.
Thus, if there were separate adult and pediatric units, the adult nurses while experienced in general epilepsy care would have little experience with the ketogenic diet whereas the pediatric nurses would have less experience with WADA tests and psychogenic seizures.
Since we have had five lifters who tested positive in the WADA tests, the possibility of ban is quite high.