WHO staging system
WHO staging system
AIDS A simplified AIDS staging system proposed by the WHO Global Programme on AIDS that is flexible enough to be used in different regions, based on 4 groups of clinical conditions that have prognostic significance and therefore constitute stages, plus an assessment of physical activity performance expressed as a 4-point score; Pts are classified according to the highest stage recorded for either clinical condition or physical activity Categories Asymptomatic; mildly symptomatic; moderately symptomatic; severely symptomatic. See AIDS, HIV-1. WHO Staging System for HIV Infection
Clinical Stage 1
1. Asymptomatic infection
.
2. Persistent generalized lymphadenopathy
.
3. Acute retroviral infection
Performance Stage 1: asymptomatic, normal activity
Clinical Stage 2
.
4. Unintentional weight loss < 10% body weight
.
5. Minor mucocutaneous manifestations (e.g., dermatitis, prurigo, fungal nail infections, angular cheilitis)
.
6. Herpes zoster within previous 5 years
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7. Recurrent upper respiratory tract infections
Performance Stage 2: symptoms, but nearly fully ambulatory
Clinical Stage 3
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8. Unintentional weight loss > 10% body weight
.
9. Chronic diarrhea > 1 month
.
10. Prolonged fever > 1 month (constant or intermittent)
.
11. Oral candidiasis
.
12. Oral hairy leukoplakia
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13. Pulmonary tuberculosis within the previous year
.
14. Severe bacterial infections
.
15. Vulvovaginal candidiasis
Performance Stage 3: in bed > normal but < 50% of normal daytime during the previous month
Clinical Stage 4
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16. HIV wasting syndrome
.
17. Pneumocystis carinii pneumonia
.
18. Toxoplasmosis of the brain
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19. Crytosporidiosis with diarrhea > 1 month
.
20. Isosporiasis with diarrhea > 1 month
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21. Cryptococcosis, extrapulmonary
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22. Cytomegalovirus disease of an organ other than liver, spleen or lymph node
.
23. Herpes simplex virus infection, mucocutaneous
.
24. Progressive multifocal leukoencephalopathy
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25. Any disseminated endemic mycois (e.g., histoplasmosis)
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26. Candidiasis of the esophagus, trachea, bronchi, or lung
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27. Atypical mycobacteriosis, disseminated
.
28. Non-typhoid Salmonella septicemia
.
29. Extrapulmonary tuberculosis
.
30. Lymphoma
.
31. Kaposi's sarcoma
.
32. HIV encephalopathy
http://hivinsite.ucsf.edu/InSite?page=kb-01-01#S4X
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.