WHO staging system

WHO staging system

AIDS A simplified  AIDS staging system proposed by the WHO Global Programme on AIDS that is flexible enough to be used in different regions, based on 4 groups of clinical conditions that  have prognostic significance and therefore constitute stages, plus an assessment of physical activity performance expressed as a 4-point score; Pts are classified according to the highest stage recorded for either clinical condition or physical activity Categories Asymptomatic; mildly symptomatic; moderately symptomatic; severely symptomatic. See AIDS, HIV-1.

WHO Staging System for HIV Infection

Clinical Stage 1

 

1.  Asymptomatic infection

 .

2.  Persistent generalized lymphadenopathy

 .

3.  Acute retroviral infection

 Performance Stage 1: asymptomatic, normal activity

Clinical Stage 2

 .

4.  Unintentional weight loss < 10% body weight

 .

5.  Minor mucocutaneous manifestations (e.g., dermatitis, prurigo, fungal nail infections, angular cheilitis)

 .

6.  Herpes zoster within previous 5 years

 .

7.  Recurrent upper respiratory tract infections

Performance Stage 2:  symptoms, but nearly fully ambulatory

Clinical Stage 3

 .

8.  Unintentional weight loss > 10% body weight

 .

9.  Chronic diarrhea > 1 month

 .

10.  Prolonged fever > 1 month (constant or intermittent)

 .

11.  Oral candidiasis

 .

12.  Oral hairy leukoplakia

 .

13.  Pulmonary tuberculosis within the previous year

 .

14.  Severe bacterial infections

 .

15.  Vulvovaginal candidiasis

Performance Stage 3: in bed > normal but < 50% of normal daytime during the previous month

Clinical Stage 4

 .

16.  HIV wasting syndrome

.

17.  Pneumocystis carinii pneumonia

 .

18.  Toxoplasmosis of the brain

 .

19.  Crytosporidiosis with diarrhea > 1 month

 .

20.  Isosporiasis with diarrhea > 1 month

 .

21.  Cryptococcosis, extrapulmonary

 .

22.  Cytomegalovirus disease of an organ other than liver, spleen or lymph node

 .

23.  Herpes simplex virus infection, mucocutaneous

 .

24.  Progressive multifocal leukoencephalopathy

 .

25.  Any disseminated endemic mycois (e.g., histoplasmosis)

 .

26.  Candidiasis of the esophagus, trachea, bronchi, or lung

 .

27.  Atypical mycobacteriosis, disseminated

 .

28.  Non-typhoid Salmonella septicemia

 .

29.  Extrapulmonary tuberculosis

 .

30.  Lymphoma

 .

31.  Kaposi's sarcoma

.

32.  HIV encephalopathy

http://hivinsite.ucsf.edu/InSite?page=kb-01-01#S4X

.

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.