WHO staging system

WHO staging system

AIDS A simplified  AIDS staging system proposed by the WHO Global Programme on AIDS that is flexible enough to be used in different regions, based on 4 groups of clinical conditions that  have prognostic significance and therefore constitute stages, plus an assessment of physical activity performance expressed as a 4-point score; Pts are classified according to the highest stage recorded for either clinical condition or physical activity Categories Asymptomatic; mildly symptomatic; moderately symptomatic; severely symptomatic. See AIDS, HIV-1.

WHO Staging System for HIV Infection

Clinical Stage 1

 

1.  Asymptomatic infection

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2.  Persistent generalized lymphadenopathy

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3.  Acute retroviral infection

 Performance Stage 1: asymptomatic, normal activity

Clinical Stage 2

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4.  Unintentional weight loss < 10% body weight

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5.  Minor mucocutaneous manifestations (e.g., dermatitis, prurigo, fungal nail infections, angular cheilitis)

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6.  Herpes zoster within previous 5 years

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7.  Recurrent upper respiratory tract infections

Performance Stage 2:  symptoms, but nearly fully ambulatory

Clinical Stage 3

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8.  Unintentional weight loss > 10% body weight

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9.  Chronic diarrhea > 1 month

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10.  Prolonged fever > 1 month (constant or intermittent)

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11.  Oral candidiasis

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12.  Oral hairy leukoplakia

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13.  Pulmonary tuberculosis within the previous year

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14.  Severe bacterial infections

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15.  Vulvovaginal candidiasis

Performance Stage 3: in bed > normal but < 50% of normal daytime during the previous month

Clinical Stage 4

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16.  HIV wasting syndrome

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17.  Pneumocystis carinii pneumonia

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18.  Toxoplasmosis of the brain

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19.  Crytosporidiosis with diarrhea > 1 month

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20.  Isosporiasis with diarrhea > 1 month

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21.  Cryptococcosis, extrapulmonary

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22.  Cytomegalovirus disease of an organ other than liver, spleen or lymph node

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23.  Herpes simplex virus infection, mucocutaneous

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24.  Progressive multifocal leukoencephalopathy

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25.  Any disseminated endemic mycois (e.g., histoplasmosis)

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26.  Candidiasis of the esophagus, trachea, bronchi, or lung

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27.  Atypical mycobacteriosis, disseminated

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28.  Non-typhoid Salmonella septicemia

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29.  Extrapulmonary tuberculosis

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30.  Lymphoma

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31.  Kaposi's sarcoma

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32.  HIV encephalopathy

http://hivinsite.ucsf.edu/InSite?page=kb-01-01#S4X

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