WDR36 | definition of WDR36 by Medical dictionary
WDR36 A gene on chromosome 5q22.1 that encodes a member of the WD-repeat protein family involved in T-cell activation and highly co-regulated with IL2.
WDR36 mutations are associated with primary open-angle glaucoma (POAG).
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References in periodicals archive
Depletion of five SSUP proteins (Imp4, Mpp10/Mphosph10, Wdr36
, Wdr46, and Wdr75) resulted in a reduction of Nanog expression, and the absence of one SSUP component (Cirh1a) caused cell death.
Primer acik acili glokomla iliskili bulunmus bir diger gen olan WDR36 5q22.1 bolgesindeki GLC1G lokusunda yer alir, ailelerin %5'i bu bolgeye baglanti gosterir.
The role of the WDR36 gene on chromosome 5q22.1 in a large family with primary open-angle glaucoma mapped to this region.