WASP Family Protein

Wiskott-Aldrich Syndrome Protein Family Member 2; Wasf-2. A downstream effector protein [MIM 605875], encoded on 1p36.11-p34.3, which is involved in transmitting signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton; it regulates actin assembly downstream of the cdc42 and phosphatidylinositol bisphosphate signalling pathways
References in periodicals archive ?
Physical mechanisms of signal integration by WASP family proteins are elucidated, and virus entry by endocytosis is described.