Significantly higher rates of pressure injuries were found in: the elderly; long-term patients; patients with acute renal failure; or volume depletion
Patients should be monitored for the development of genital and urinary tract infections and signs of volume depletion
during treatment with SGLT-2 inhibitors.
Adverse events related to osmotic diuresis and volume depletion
are among the most common.
Hyponatremia was likely multifactorial and includes continuing free water intake in the presence of enhanced secretion of antidiuretic hormone (ADH) with volume depletion
and/or inappropriate ADH secretion in the setting of nausea, "beer potomania," and small degree of hyperglycemia-induced extracellular free water shift.
Hyponatremia in patients with cancer may be associated with volume depletion
due to gastrointestinal fluid losses and poor oral fluid intake.
As unilateral renal function is being recovered, general conditions including volume depletion
and metabolic acidosis are normalizing promptly.
Side-effects and half-life of diuretics Diuretic Side-effect Half-life Loop * Electrolyte imbalance Oral bioavailability * Hypokalaemia between 10% and 90% * Volume depletion
Acts at luminal side (prerenal uraemia) of the thick ascending * Tinnitus (acts within limb (NaK2Cl transporter) the cochlea--can Highly protein bound synergise with Rebound after single aminoglycoside dose T1/2: 4 hours antibiotics Thiazide Metabolic T1/2: 3-5 hours * Hyperuricaemia, impaired glucose tolerance and electrolyte disturbances (hypokalaemia and hyponatraemia) * Volume depletion
Yet, findings could be interpreted in that moderate and careful volume and substitution may be preferable over strict volume depletion
in this highly febrile disease as it may not only improve cardiac output but also may have a beneficial effect on microcirculation, tissue perfusion and lactic acidosis.
The studies examined the effects of these various intravenous solutions on relative blood volume (RBV), blood pressure (BP) and the relief of symptoms of volume depletion
in people receiving HD treatment.
Unfortunately, the story is a little more complex, because volume depletion
is a secondary stimulus for vasopressin release.
There may be intravascular volume depletion
and evidence of hypovolaemic shock.
The definition offered by San Miguel (2010) is "target weight or ideal weight is the weight the clinician hopes a patient will be at the end of each hemodialysis treatment without suffering any of the intradialytic complications associated with intravascular volume depletion