[sz]-blockers and volatile anesthetics
may attenuate cardioprotection by remote preconditioning in adult cardiac surgery: A meta-analysis of 15 randomized trials.
Multiple studies have shown the potential benefits of volatile anesthetics
over the intravenous anesthetics in cardiac surgery .
Differential protective effects of volatile anesthetics
against renal ischemia-reperfusion injury in vivo.
So modern machines like Draeger and Datex Ohmeda were introduced which were not only fitted by gas, O2 special bottles of volatile anesthetic
agents, but also by ventilator, close circuit apparatus with soda lime , cardiac monitors, pulse oxymeters and what not.
Relative to other volatile anesthetics
(e.g., desflurane, sevoflurane), isoflurane has a higher blood-gas partition coefficient (1.4) and, thus, a longer recovery time.
(1,2,8) In addition to the immediate termination of a volatile anesthetic
, other management steps include the commencement of mechanical ventilation with 100% oxygen at a flow rate greater than 10 L/min, normalization of metabolic derangements, and a lowering of body temperature with topical ice or ice-water lavage.
It reduces the requirements for volatile anesthetics
, sedatives and analgesics without causing significant respiratory depression.
In the presence of a volatile anesthetic
mixture, electrocautery can result in the ignition of plastic, rubber, paper, and other combustible or flammable materials.
Notwithstanding the limitations of the studies so far completed, most of them show the superiority of volatile anesthetics
against the traditional intravenous drugs for ICU sedation.
Of all the available volatile anesthetic
agents, Halothane is the cheapest and the most commonly available volatile agent in developing countries.
Predictive accuracy of a model of volatile anesthetic
* Dion's Formula: Usage of volatile anesthetic
(mL) = [Dialed concentration x Total fresh gas flow x Duration at that concentration x Molecular weight]/[2412 x Density].