There was presence of vitreous seeding
on examination in seven cases.
Because the vitreous is an avascular tissue and the systemic or intra-arterial administration of chemotherapy has limited transition to the vitreous, vitreous seeding is an especially important problem.
Intravitreal melphalan for refractory or recurrent vitreous seeding from retinoblastoma.
Combined intravitreal melphalan and topotecan for refractory or recurrent vitreous seeding from retinoblastoma.
We report a case with whitish, elevated, vascularized retinal mass and vitreous seeding diagnosed as undifferentiated retinoblastoma.
As malignant retinal tumor with vitreous seeding of the left eye was diagnosed, the patient was informed sufficiently and decided to receive enucleation.
Characteristic manifestation of these adult retinoblastoma was whitish, elevated, vascularized retinal mass with vitreous seeding.
A small raised mass usually can be seen on the retina, with possible vitreous seeding.
5 mm in height can be treated successfully with this technique; however, the procedure is not undertaken if vitreous seeding is present.
Her right eye was blind and there was vitreous seeding
in the left eye (group Vb), where some useful vision remained.
In some instances, vitreous seeding
may be extensive and allow tumour cells to be visible as spheroid masses floating in the vitreous and anterior chamber, simulating endophthalmitis or iridocyclitis, and obscuring the primary mass.
High-risk features evaluated included the presence and extent of optic nerve (ON) invasion with respect to lamina cribrosa, the status of the ON cut margin, the presence of vitreous seedings
, and invasion of the sclera, anterior chamber, and choroid.