Vistaril


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Related to Vistaril: hydroxyzine

Vistaril

 [vis´tah-ril]
trademark for preparations of hydroxyzine, an antianxiety agent, antiemetic, sedative, and antipruritic.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

hydroxyzine hydrochloride

Apo-Hydroxyzine (CA), Atarax (CA) (UK), Novo-Hydroxyzin (CA), Nu-Hydroxyzine (CA), PMS-Hydroxyzine (CA), Riva-Hydroxyzine (CA), Ucerax (UK)

hydroxyzine pamoate

Vistaril

Pharmacologic class: Piperazine derivative

Therapeutic class: Anxiolytic, antihistamine, sedative-hypnotic

Pregnancy risk category NR

Action

Unknown. Anxiolytic and sedative effects may stem from suppression of activity in subcortical levels of CNS. Antihistamine effects may result from histamine suppression at cellular receptor sites.

Availability

Capsules: 25 mg, 50 mg, 100 mg (pamoate)

Injection: 25 mg/ml, 50 mg/ml

Oral suspension: 25 mg/5 ml (pamoate)

Syrup: 10 mg/5 ml

Tablets: 10 mg, 25 mg, 50 mg

Indications and dosages

Psychiatric emergencies; acute or chronic alcoholism

Adults: 50 to 100 mg I.M. immediately, then q 4 to 6 hours p.r.n.

Nausea and vomiting; adjunct in pre- and postoperative sedation

Adults: 25 to 100 mg I.M. q 4 to 6 hours

Children: 1.1 mg/kg I.M. q 4 to 6 hours

Anxiety

Adults and children ages 6 and older: 50 to 100 mg P.O. q.i.d.

Children younger than age 6: 50 mg P.O. daily in divided doses

Pruritus

Adults: 25 mg P.O. three or four times daily

Children ages 6 and older: 50 to 100 mg P.O. daily in divided doses

Children younger than age 6: 50 mg P.O. daily in divided doses

Off-label uses

• Seasonal allergic rhinitis

Contraindications

• Hypersensitivity to drug or cetirizine

• Early pregnancy

Precautions

Use cautiously in:

• severe hepatic dysfunction

• elderly patients.

Administration

Don't administer I.V. or subcutaneously (may cause tissue necrosis).

• Use Z-track method for I.M. injection. Inject deep into large muscle (preferably, upper outer quadrant of buttock).

Adverse reactions

CNS: drowsiness, agitation, dizziness, headache, asthenia, ataxia

GI: nausea, constipation, dry mouth

GU: urinary retention

Respiratory: wheezing

Skin: flushing

Other: bitter taste, hypersensitivity reaction, pain or abscess at I.M. injection site

Interactions

Drug-drug. Anticholinergics, anti-depressants, antihistamines, phenothiazines, quinidine: additive effects of these drugs

Antidepressants, antihistamines, opioids, sedative-hypnotics, other CNS depressants: additive CNS depression

Drug-diagnostic tests. Skin tests using allergen extracts: false-negative results

Drug-herbs. Angel's trumpet, jimsonweed, scopolia: increased anticholinergic effects

Chamomile, hops, kava, skullcap, valerian: increased CNS depression

Drug-behaviors. Alcohol use: increased CNS depression

Patient monitoring

• Monitor closely for CNS depression and oversedation, especially if patient is receiving other CNS depressants.

• Assess for adverse effects, especially in elderly patients.

• Monitor liver function test results in patients with hepatic impairment.

Patient teaching

• Tell patient to contact prescriber if he experiences wheezing, muscle spasms, or incoordination.

• Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.

• Instruct patient to avoid alcohol while taking drug.

• As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs, tests, herbs, and behaviors mentioned above.

McGraw-Hill Nurse's Drug Handbook, 7th Ed. Copyright © 2013 by The McGraw-Hill Companies, Inc. All rights reserved

Vistaril

(vĭs′tə-rĭl′)
A trademark for a drug preparation of hydroxyzine.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Vistaril®

Hydroxyzine, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
One said: Deputies and a nurse ordered Vistaril and Phenergan.
Another said: The counselor or the jail nurse put me on Vistaril and Elavil.
decided I had to be on Mellaril, Lithium, Elavil, Sinequan, Vistaril, I didn't want to take it.
A 1997 study of pregnant women found no significant difference in the rates of major or minor malformations, gestational age at delivery, birth weight, or neonatal distress among 39 women who took cetirizine (most included first-trimester use), 81 women who took hydroxyzine (Vistaril or Atarax), and 110 controls who did not take either agent.
The trial court also inquired as to whether Moran was "presently under the influence of any drug or alcohol," to which Moran responded, "[j]ust what they give me in, you know, medications."(130) At the time, Moran was being administered simultaneously four types of medications--phenobarbital, dilantin, inderal, and vistaril.(131) Later testimony revealed that the drugs had a "numbing effect" on Moran; he stated that he did not care about the proceedings or anything else that was going on.(132) The trial court, however, made no further inquiry or investigation into either the dosages or the type of medication Moran was taking.(133)
The dissent noted that Moran's medical records "show that Moran was administered dilantin, an anti-epileptic medication that may cause confusion; inderal, a beta-blocker anti-arrhythmic that may cause light-headedness, mental depression, hallucinations, disorientation, and short-term memory loss; and vistaril, a depressant that may cause drowsiness, tremors, and convulsions." Id.
Generic Trade Name Daily Dose Estazolam Prosom 1(*) Lorazepam(**) Ativan 2 Oxazepam(**) Serax 30 Alprazolam(**) Xanax 0.75 (Panic Attack: 2-6) Buspirone Buspar 30 Diphenhydramine(***) Benadryl 50 Hydroxyzine(***) Atarax/ 50 Vistaril Chloral Hydrate(***) 750 * Added by JW Cooper to correct omission in OBRA.
Nurses gave the patient intramuscular injections of pain medications Demerol and Vistaril in the patient's legs, buttocks, and shoulder throughout her hospitalization.
After 2 days, we discharge patients on oral metoclopramide and hydroxyzine (Vistaril) four times a day
Nevertheless, they should be avoided if possible during the first trimester because of the sparse amount of data in humans on use of these drugs during pregnancy These data include a 1997 study of pregnant women that found no significant difference in the rates of major or minor malformations, gestational age at delivery, birth weight, or neonatal distress among 39 women who took cetirizine (most included first-trimester use), 81 women who took hydroxyzine (Vistaril or Atarax), and 110 controls who did not take either agent.