Virtual Biopsy

The use of an imaging modality (e.g., ultrasonography, functional MRI, or virtual biopsy colonoscopy—a direct visualisation technique coupled with a probe-based Confocal Laser Endomicroscope—pCLE) to localise a tumour and assess its physical features
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NM-01 could provide a specific, non-invasive approach to diagnosis, including use in whole-body imaging, or virtual biopsy. NM-01 potentially allows detection of PD-L1 expression in immuno-oncology studies, either before or during immuno-oncology treatment.
(19-21) More recent data using commercially-available second generation swept source OCT (SS-OCT) technology have shown the potential of OCT to obtain virtual biopsy cores through a needle.
The biopsies were performed in a targeted manner on 12 virtual biopsy targets that were arranged in a standard 12-core sextant scheme with medial and lateral targets defined for each region.