LL lesions were characterized by massive macrophage inltration containing a variable number of Virchow cells
, full of bacilli accompanied by few lymphocytes, separated from the at epidermis by a clear zone.
The histopathological erythematous-edematous plaque (performed in the patient's arm) revealed diffuse histiocytic infiltrate, rich in foamy cells (Virchow cells) with perineural involvement, perivascular, and periannexal (Figure 5).
Histopathological showing diffuse histiocytic infiltrate, rich in foamy cells (Virchow cells) with perineural involvement, perivascular, and periannexal.
However, we noticed that both Virchow cells with a vacuolated aspect and spindle storiform cells (present in the histoid form) were positive for CD68 (Figures 2a, 2b).
The infiltrate consists of spindle histiocytes arranged along Virchow cells. The amount of AFB in the histoid form is large compared with the lepromatous form.
A skin biopsy from the knee showed Virchow cells containing multiple AFB and areas with tuberculoid granulomas (Figures 3A and 3B).
There were no Virchow cells. Scanty AFB were seen on Wade staining.