moxifloxacin

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moxifloxacin

 [mok″sĭ-flok´sah-sin]
a broad-spectrum antibiotic effective against many gram-positive and gram-negative bacteria; administered orally as the hydrochloride salt in the treatment of bacterial complication of chronic bronchitis, acute sinusitis, community-acquired pneumonia, and skin and skin structure infections due to susceptible organisms.

moxifloxacin

(mŏk′sĭ-flŏk′sə-sĭn)
n.
An antibiotic drug of the fluoroquinolone class, C21H24FN3O4, used primarily to treat respiratory, sinus, and skin infections.

moxifloxacin

A fluoroquinolone wide-spectrum antibiotic with activity against both Gram positive and Gram negative organisms. A brand name is Avelox.

antibiotic 

1. Pertaining to the ability to destroy or inhibit other living organisms.
2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.
References in periodicals archive ?
Moxifloxacin belongs to a group of broad-spectrum antibiotics called fluoroquinolones and is available as an oral tablet (Avelox) and an eye drop (Vigamox).
as Vigamox, is approved for children aged 1 year and older and adults for the treatment of bacterial conjunctivitis caused by moxifloxacin-susceptible organisms.
Postoperative topical therapy included topical prednisolone (1%, Pred Forte, Allergan), moxifloxacin (0.5%, Vigamox, Alcon), and nepafenac (0.1%, Nevanac, Alcon).
Some of Lupin's recent generic launches include Fayosim Tablets USP (Quartette); Desoximetasone Ointment USP, 0.05% and 0.25% (Topicort); Desoximetasone Cream USP, 0.05% and 0.25% (Topicort LP Emollient Cream (0.05%); Topicort Cream (0.25%); Bupropion Hydrochloride Extended-Release Tablets USP (XL) (Wellbutrin XL); Moxifloxacin Ophthalmic Solution 0.5% (Vigamox); and Quetiapine Fumarate Extended-Release Tablets (Seroquel XR).
Antibiotic moxifloxacin (Vigamox 0.05%, Alcon) and lubricants hypromellose, (Tear Naturale II, Alcon) were advised for one week.
Vigamox Ophthalmic Solution (moxifloxacin ophthalmic solution 0.5%, Alcon Inc.)
A single drop of antibiotic (Vigamox Alcon Belgium) is instilled and patients were instructed to administer topical antibiotics for one week.
All patients were treated postoperatively with topical moxifloxacin 0.5% (Vigamox, Alcon Laboratories) applied 4 times daily up to 2 weeks.
Postoperatively, all patients were treated with topical 0.5% moxifloxacin (Vigamox 0.5% sterile ophthalmic solution, Alcon) 6 times daily for 3 weeks and artificial tears for approximately 1 year.
The patient was administered moxifloxacin ophthalmic drops (Vigamox 0.5%; Alcon Laboratories Inc., Fort Worth, TX, USA) 4 times a day for 3 weeks and preservative-free artificial tears (Tears Naturale Free; Alcon Laboratories Inc., Fort Worth, TX, USA) 4 times a day for 4 weeks.
Postoperative medication included moxifloxacin 0.5% (Vigamox, Alcon, Inc., Canada) 4 times a day for one week and artificial tears 4 times a day for one month postoperatively.