vigabatrin


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Related to vigabatrin: Tiagabine

vig·a·bat·rin

(vī-ga'bă-trin),
An irreversible inhibitor of γ-aminobutyric acid transaminase, a degradative enzyme for γ-aminobutyric acid (GABA), the inhibitory neurotransmitter. The drug intensifies the effects of GABA and thus inhibition of the central nervous system; used as an antiepileptic agent.

vigabatrin

Gamma-vinyl GABA, Sabril® Pharmacology A 2nd-line antiepileptic used for convulsions or seizures refractory to other agents Adverse effects Somnolence, stupor, hyperkinesia, insomnia, ↑ weight, facial edema

vigabatrin

A drug that simulates the action of the NEUROTRANSMITTER GABA and is used to treat EPILEPSY resistant to other controlling agents. A brand name is Sabril.

vig·a·bat·rin

(vī-ga'bă-trin)
An antiepileptic agent.
References in periodicals archive ?
Reddy's') today announced the launch of Vigabatrin Powder for Oral Solution, USP in 500 mg per packet, a therapeutic equivalent generic version of Sabril (vigabatrin) Powder for Oral Solution, USP, approved by the U.S.
Labeling for vigabatrin tablets includes a boxed warning for permanent vision loss.
This US FDA's approval of generic vigabatrin tablets was granted to Teva Pharmaceuticals USA.
KEYWORDS: Epileptic Encephalopathies, Electroencephalographic, Hypsarrythmia, Myoclonic jerks, Vigabatrin.
Aucta's commercial partner, UpsherSmith Laboratories, LLC, will launch vigabatrin for oral solution under the brand name Vigadrone, a substitutable generic alternative to Sabril (vigabatrin) powder for oral solution.
The area of isopters obtained by SKP has already been measured in patients suffering from advanced glaucoma, retinal dystrophies, and neuroophtalmological diseases [30], as well as epilepsy patients treated with vigabatrin [31].
Avoid these enzyme-inducing Consider these non-enzyme-inducing antiepileptic drugs antiepileptic drugs * Carbamazepine (Tegretol) * Ethosuximide (Zarontin) * Felbamate (Felbatol) * Gabapentin (Neurontin) * Lamotrigine (Lamictal) * Levetiracetam (Keppra) * Oxcarbazepine (Trileptal) * Pregabalin (Lyrica) * Phenobarbital (Luminal) * Tiagabine (Gabitril) * Phenytoin (Dilantin) * Valproate (Depakote) * Primidone (Mysoline) * Vigabatrin (Sabril) * Topiramate (Topamax) * Zonisamide (Zonegran) * Benzodiazepines OCs, oral contraceptives.
She was treated with vigabatrin with excellent clinical and electrophysiologic response.
Once a diagnosis of WS is confirmed, adrenocorticotropic hormone (ACTH) and vigabatrin are prescribed.
Vigabatrin ve adrenokortikotropik hormon tedavilerine ragmen neredeyse hic fayda gormemis ve 150/gun siklikta spazm sayisi ile izlenirken VSU uygulamasi sonrasi nobet sayisinda ilk 6 ayda %96 azalma saptandi.
Vigabatrin is recommended as the first-line treatment for infantile (epileptic) spasms.
Al cuarto mes de edad presento espasmos infantiles y se inicio tratamiento con piridoxina y vigabatrin; ha tenido multiples hospitalizaciones, mal control de las crisis epilepticas y presencia de otras crisis como ausencias, caida cefalica y focales motoras, por lo que fue necesario hacer ajustes en el tratamiento con vigabatrin, clobazam, acido valproico y levetiracetam, con los que se controlaron los espasmos.