Vicodin


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hydrocodone bitartrate and acetaminophen

Anexsia, Ceta-Plus, Co-Gesic, Hydrocet, Lortab, Norco, Stagesic, Vicodin, Vicodin ES, Vicodin HP, Xodol, Zydone

hydrocodone bitartrate and aspirin


hydrocodone bitartrate and ibuprofen

Vicoprofen

hydrocodone bitartrate and homatropine methyl-bromide

Hycodan

Pharmacologic class: Opioid agonist/nonopioid analgesic combination

Therapeutic class: Opioid analgesic; allergy, cold, and cough remedy (antitussive)

Controlled substance schedule III

Pregnancy risk category C

Action

Blocks release of inhibitory neurotransmitters, altering perception of and emotional response to pain. Hydrocodone/ibuprofen combination raises pain threshold by nonselectively inhibiting cyclooxygenase; prostaglandin synthesis then decreases and anti-inflammatory and analgesic effects occur.

Availability

hydrocodone bitartrate and acetaminophen

Capsules: 5 mg hydrocodone (hyd.)/500 mg acetaminophen (acet.)

Elixir/oral solution: 2.5 mg hyd./167 mg acet./5 ml

Tablets: 2.5 mg hyd./500 mg acet.; 5 mg hyd./325 mg acet.; 5 mg hyd./400 mg acet.; 5 mg hyd./500 mg acet.; 7.5 mg hyd./325 mg acet.; 7.5 mg hyd./400 mg acet.; 7.5 mg hyd./500 mg acet.; 7.5 mg hyd./650 mg acet.; 7.5 mg hyd./750 mg acet.; 10 mg hyd./325 mg acet.; 10 mg hyd./400 mg acet.; 10 mg hyd./500 mg acet.; 10 mg hyd./650 mg acet.; 10 mg hyd./660 mg acet.; 10 mg hyd./750 mg acet.

hydrocodone bitartrate and aspirin

Tablets: 5 mg hyd./500 mg aspirin

hydrocodone bitartrate and ibuprofen

Tablets: 7.5 mg hyd./200 mg ibuprofen

hydrocodone bitartrate and homatropine methylbromide

Syrup: 1.5 mg/5 ml, 5 mg/5 ml

Tablets: 1.5 mg, 5 mg

Indications and dosages

Moderate to severe pain

Adults: 2.5 to 10 mg P.O. q 4 to 6 hours p.r.n. When giving hydrocodone/acetaminophen, don't exceed 60 mg/day; when giving hydrocodone/ibuprofen, don't exceed 37.5 mg/day.

Children: 0.15 to 0.2 mg/kg P.O. q 6 hours

Cough

Adults: One tablet or 5 ml (syrup) q 4 to 6 hours as needed; don't exceed 6 tablets or 30 ml syrup in 24 hours.

Children ages 6 to 12: One-half tablet or 2.5 ml (syrup) q 4 to 6 hours as needed; don't exceed 3 tablets or 15 ml syrup in 24 hours.

Contraindications

• Hypersensitivity to hydrocodone, acetaminophen, aspirin, ibuprofen, or homatropine methylbromide (for corresponding combination products) or to alcohol, aspartame, saccharine, sugar, or tartrazine (with some products)

Precautions

Use cautiously in:

• severe renal, hepatic, or pulmonary disease; increased intracranial pressure; hypothyroidism; adrenal insufficiency; prostatic hypertrophy; thrombocytopenia; alcoholism

• elderly patients

• pregnant or breastfeeding patients.

Administration

In patients receiving concurrent MAO inhibitors, know that hydrocodone may produce severe, unpredictable reactions. Initial dosage may need to be 25% lower than usual dosage.

Adverse reactions

CNS: confusion, drowsiness, sedation, dysphoria, euphoria, floating feeling, hallucinations, headache, anxiety, depression, fatigue, insomnia, lethargy, nervousness, slurred speech, tremor, asthenia, unusual dreams

CV: orthostatic hypotension, bradycardia, peripheral edema, palpitations, arrhythmias

EENT: blurred vision, vision changes, diplopia, miosis, tinnitus, pharyngitis, rhinitis, sinusitis

GI: nausea, vomiting, constipation, dysphagia, esophagitis, dyspepsia, flatulence, gastritis, gastroenteritis, mouth ulcers, dry mouth, anorexia

GU: urinary retention or frequency, erectile dysfunction

Respiratory: respiratory depression, bronchitis, dyspnea

Skin: pruritus, urticaria, diaphoresis, flushing

Other: physical or psychological drug dependence, drug tolerance

Interactions

Drug-drug. Angiotensin-converting enzyme inhibitors: decreased therapeutic effects of these drugs

Antihistamines, sedative-hypnotics: additive CNS depression

Buprenorphine, butorphanol, nalbuphine, pentazocine: precipitation of opioid withdrawal in physically dependent patients

Buprenorphine, pentazocine: decreased analgesia

Lithium: increased lithium blood level (with hydrocodone/ibuprofen only)

MAO inhibitors: severe, unpredictable reactions

Methotrexate: increased methotrexate blood level

Naloxone: withdrawal symptoms

Oral anticoagulants: increased risk of GI bleeding (with hydrocodone/ibuprofen only)

Drug-diagnostic tests. Amylase, lipase: increased levels

Drug-herbs. Chamomile, hops, kava, skullcaps, valerian: increased CNS depression

Drug-behaviors. Alcohol use: increased CNS depression

Patient monitoring

• In prolonged use, monitor for psychological and physical dependence.

• Watch closely for withdrawal symptoms when drug is discontinued.

• Assess elderly patients carefully for adverse reactions.

Monitor for signs and symptoms of drug overdose, including nausea, vomiting, blurred vision, cool and clammy skin, dizziness, confusion, dyspnea, respiratory depression, bradycardia, hearing loss, tinnitus, headache, and mood or behavior changes.

Patient teaching

• Tell patient drug may cause drowsiness. Caution him to avoid driving and other hazardous activities until CNS effects are known.

• Inform patient that prolonged use may lead to physical or psychological dependence.

• Caution patient to avoid alcohol during therapy.

• Instruct patient to move slowly when sitting up or standing, to avoid dizziness from sudden blood pressure decrease.

• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, herbs, and behaviors mentioned above.

Vicodin

(vī′kə-dn)
A trademark for a drug containing hydrocodone bitartrate and acetaminophen.

Patient discussion about Vicodin

Q. what about opiod use in anxiety and depression? vicodin, anxiety, depression

A. START EDUCATING YOUR SELFS ON PRESCRIPTION DRUGS.MOST OF THE TIME THEY DO MORE HARM THAN GOOD,GO ON THE INTERNET AND REALLY CHECK YOUR PRESCRIPTION DRUGS AND IF THEY ARE BEING PRESCRIBED FOR OFF LABEL USE.

Q. Does anyone have information on Bipolar "blackouts" or know what they're really called? My boyfriend is bipolar and experienced a blackout a few weeks ago during which he did something completely out of character. A crime was committed and he has since been arrested. He's having trouble coping as he has no memory of the crime. He was on Wellbuterin and a doctor prescribed steroids and vicodin for a crushed disc. The chemicals may have led him into this blackout. He is a wonderful loving person and is now facing a life sentence for this terrible thing that happened that he had no conscious control over. They will not continue his medications in jail and he is not receiving mental or medical treatment. Is there anyone out there that can help me find some answers?

A. i never heard of such thing. but there are strange results sometimes from mixing drugs that affect the central nervous system. here is for instance a web page talking about interactions between Vicodin and Wellbutrin.

http://www.drugs.com/drug_interactions.php

More discussions about Vicodin
References in periodicals archive ?
The star spent time in and out of rehab but has now been sober for 17 years, since flying to an LA facility in 2001 for addiction to Vicodin, amphetamines, methadone and alcohol.
Favre said he was first admitted to rehab for 28 days to treat an addition to prescription pills, saying on one occasion he had taken 12 Vicodin tablets at once.
Frequency and descriptive statistics were used to examine 12-month use rates for Oxycontin, Vicodin, and daily ED and ES use.
The Food and Drug Administration (FDA) agency warned that combining Xanax - used to treat depression - and the opioid Vicodin "may result in profound sedation, respiratory depression, coma, and death," the (http://nypost.com/2017/06/09/tiger-woods-told-cops-he-took-xanax-vicodin-on-night-of-dui-arrest-report/) New York Post reported.
The vast majority of participants used opioids such as Oxycontin, Percocet, and Vicodin for a short period, and then stopped, according to a paper published online in the Aug.
Let's use an example to illustrate each of these: If a patient comes to you asking for Vicodin (hydrocodone and acetaminophen) because you froze actinic keratoses, your first instinct might be to think this patient is a drug seeker and that he is not going to be satisfied unless you give in to his demand.
In this instance, ask him why he wants Vicodin; probe about issues that might underlie his request.
The former Friends star went to rehab for a Vicodin addiction in 1997 and then again for alcohol and prescription drugs therapy in 2001.
All these pies I've been baking, but also the Vicodin cure I've been studying since she gave me the clap last winter and it felt like someone had taken a hammer to my balls.
Past-year use of the opioid pain reliever Vicodin shows a significant five-year drop, with 4.8% of 12th-graders using Vicodin for nonmedical reasons, half of what it was five years ago.
The treatment provides an alternative for patients who take various medications, including sleep medications, dopaminergic agents, such as amphetamines, anticonvulsants, such as gabapentin (Neurontin), opioids, such as hydrocodone (Vicodin), or muscle relaxants, such as carisoprodol (Soma), or who must get up in the night and move their legs to relieve symptoms, thus losing sleep.
The new rules mean that drugs such as Vicodin, Lortab and their generic equivalents will be subject to the same prescribing rules as painkillers such as codeine and oxycodone.