Verocay bodies

Ver·o·cay bod·ies

hyalinized acellular areas composed of reduplicated basement membrane outlined by opposing rows of parallel nuclei; seen microscopically in schwannoma.


José, Czech pathologist, 1876-1927.
Verocay bodies - hyalinized acellular areas seen microscopically in neurilemomas.
References in periodicals archive ?
2) The Antoni A region is a hypercellular zone whose cells are fusiform with nuclei arranged in palisade forming parallel rows and producing the Verocay bodies.
Histopathologically gastrointestinal schwannoma are spindle shaped cells with a prominent lymphocytic cuff and are characterized by the absence of typical Verocay bodies, Antoni A and Antoni B areas10.
Scattered prominent Verocay bodies were also identified (Fig 5).
Palisaded nuclei and acellular reticular fibres in between these nuclei form Verocay bodies but are ill defined usually.
Caption: Figure 4: Histological images: (a) intense nuclear atypia (hematoxylin and eosin stain, x100), (b) Verocay bodies (hematoxylin and eosin stain, x100), (c) immunohistochemical reaction for S-100, and (d) immunohistochemical reaction for vimentin.
Antoni A areas were composed of spindle-shaped cells forming Verocay bodies.
Unlike conventional schwannomas, they are uncircumscribed, infiltrate around and between individual crypts, and lack cellular atypia, a lymphoid cuff, and prominent Verocay bodies (11, 12) (Figure 1, C).
The first Antoni A pattern showed closely arranged bundles of schwann cells with spindle-shaped nuclei which were aligned in parallel rows, which formed a typical palisading pattern around acellular, amorphous, eosinophilic masses, which represented the verocay bodies.
The histopathological report showed an arrangement of spindle cells in a storiform pattern with Verocay bodies interspersed with myxomatous areas.
Schwannomas are peripheral nerve sheath tumors that, in contrast to neuromas, have thick collagenous capsules, true Verocay bodies, and hypocellular or myxoid (Antoni B) stroma (3).
Microscopic findings showed fascicles of spindle shaped cells with Verocay bodies consistent with a diagnosis of a schwannoma.
Those elements are Antoni A tissue, composed of closely packed spindle shaped cells arranged in a palisading network; Antoni B tissue that is far less organized, consisting of myxoid tissue with cystic spaces and sparsely populated with cells; and Verocay bodies that are linear arrays of spindle cell nuclei.