varicella zoster virus

(redirected from Varicella-zoster)
Also found in: Dictionary, Thesaurus.
Related to Varicella-zoster: shingles

varicella zoster virus (VZV)

Etymology: L, varius, diverse; Gk, zoster, girdle; L, virus, poison
a member of the herpesvirus family, which causes the diseases varicella (chickenpox) with primary infection and herpes zoster (shingles) of the virus reactivator. The virus has been isolated from vesicle fluid in chickenpox, is highly contagious, and may be spread by direct contact or droplets. Dried crusts of skin lesions do not contain active virus particles. Herpes zoster is produced by reactivation of latent varicella virus, usually several years after the initial infection. There is no simple test for measuring antibodies to this virus. However, zoster immune globulin (ZIG) obtained from convalescing zoster patients, if injected within 3 days of exposure, will prevent varicella in susceptible children. The temporary nature of this protection and the relative scarcity of ZIG warrant reservation of its use to children receiving immunosuppressive therapy or suffering from immune deficiency diseases. Herpes zoster should be treated promptly with acyclovir, desciclovir, valaciclovir, or penciclovir to speed healing. (Famciclovir is used for postherpetic neuralgia.) A licensed vaccine is available and highly effective. See also chickenpox, herpes zoster.
References in periodicals archive ?
Schimpff S, Serpick A, Stoler B, et al: Varicella-Zoster infection in patients with cancer.
He examined data from 25 earlier studies on varicella-zoster virus in a variety of countries around the world, and plotted these data against a range of climatic factors, the BBC reported.
Natural history and treatment of varicella-zoster in high-risk populations.
Shingles lesions contain active viral particles from exposure to which a susceptible person can contract the original disease: varicella-zoster (chickenpox).
Restriction fragment length polymorphism of polymerase chain reaction products from vaccine and wild-type varicella-zoster virus isolates.
Nearly equal proportions of cases and controls (76%) recalled having had primary infection with varicella-zoster virus (Arch.
The researchers, from Oregon Health & Science University, USA, evaluated 630 blood samples from 45 people to determine the level of immunity in each individual for smallpox, measles, mumps, rubella, varicella-zoster virus, Epstein-Barr virus, tetanus and diphtheria for a period of up to 26 years.
The AtheNA Multi-Lyte MMRV test system is intended for the qualitative detection of IgG class antibody to measles, mumps, rubella, and varicella-zoster in human serum simultaneously in a single well.
Tai chi may help older adults avoid getting shingles by increasing immunity to the varicella-zoster virus and boosting the immune response to varicella vaccine, according to a new study.
Tai Chi, a traditional Chinese form of exercise, may help older adults avoid getting shingles by increasing immunity to varicella-zoster virus (VZV) and boosting the immune response to varicella vaccine in older adults, according to a new study published in print this week in the Journal of the American Geriatrics Society.
Detection of varicella-zoster virus DNA in human geniculate ganglia by polymerase chain reaction.
Whether a recent varicella-zoster reactivation in the trigeminal distribution may have occurred remains a possibility, although the tissue pathology did not disclose evidence of shingles, such as multinucleated giant cells.