varicella zoster virus

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Related to Varicella-zoster: shingles

varicella zoster virus (VZV)

Etymology: L, varius, diverse; Gk, zoster, girdle; L, virus, poison
a member of the herpesvirus family, which causes the diseases varicella (chickenpox) with primary infection and herpes zoster (shingles) of the virus reactivator. The virus has been isolated from vesicle fluid in chickenpox, is highly contagious, and may be spread by direct contact or droplets. Dried crusts of skin lesions do not contain active virus particles. Herpes zoster is produced by reactivation of latent varicella virus, usually several years after the initial infection. There is no simple test for measuring antibodies to this virus. However, zoster immune globulin (ZIG) obtained from convalescing zoster patients, if injected within 3 days of exposure, will prevent varicella in susceptible children. The temporary nature of this protection and the relative scarcity of ZIG warrant reservation of its use to children receiving immunosuppressive therapy or suffering from immune deficiency diseases. Herpes zoster should be treated promptly with acyclovir, desciclovir, valaciclovir, or penciclovir to speed healing. (Famciclovir is used for postherpetic neuralgia.) A licensed vaccine is available and highly effective. See also chickenpox, herpes zoster.
References in periodicals archive ?
Immunoelectron microscopy for rapid diagnosis of varicella-zoster virus in a complicated case of human T-cell lymphotropic virus type 1 infection.
If and when varicella-zoster reappears in the form of shingles, it takes a heavy toll.
A similar case report by Pui JC (8) detected the varicella-zoster virus in the muscularis propria layer of the terminal ileum in an HIV-positive patient who presented with the signs and symptoms of intestinal pseudo-obstruction.
Chickenpox is caused by primary infection with the varicella-zoster virus (VZV), which can remain dormant in nerve tissue.
To the Editor: Varicella-zoster virus (VZV), a human herpesvirus, is the causative agent of varicella (chickenpox) and herpes zoster (shingles).
Nearly equal proportions of cases and controls (76%) recalled having had primary infection with varicella-zoster virus (Arch.
Varicella-zoster virus (VZV) is the etiological agent of primary varicella (chicken pox) in childhood; it establishes a latent infection that may be reactivated to cause herpes zoster (shingles).
The researchers, from Oregon Health & Science University, USA, evaluated 630 blood samples from 45 people to determine the level of immunity in each individual for smallpox, measles, mumps, rubella, varicella-zoster virus, Epstein-Barr virus, tetanus and diphtheria for a period of up to 26 years.
Recent advances in varicella-zoster virus infection.
Because of lower-than-expected yields of varicella-zoster virus (VZV), which is used to manufacture the Varivax, zoster (Zostavax), and ProQuad vaccines, their manufacturer, Merck & Co.
Tai chi may help older adults avoid getting shingles by increasing immunity to the varicella-zoster virus and boosting the immune response to varicella vaccine, according to a new study.