Previous publications demonstrated a clear clinical need, showing that unidentified vanishing twins caused a significant proportion (up to 15%) of false positive NIPT results.
Panorama solves that problem by leveraging a unique SNP-based technology (single-nucleotide polymorphisms) to recognize the presence of additional DNA signatures, thereby eliminating the error rates associated with vanishing twins.
This is the first peer-reviewed publication detailing the clinical identification of vanishing twin and triploid cases by NIPT.
14), (15) Singletons who survive vanishing twins may also be more likely to have problems like those typically seen in multiples, including lower birth weight.
Consequences of vanishing twins in IVF/ ICSI pregnancies.
Since vanishing twins have been shown by other investigators to be detrimental to the surviving fetus, "our results are yet another argument for elective single embryo transfer," she said.
Her study included 1,432 singleton pregnancies, with or without vanishing twins.
The phenomenon of vanishing male conceptuses may be compared with that of vanishing twins
, due to twins disappearing before they are clinically recognized [twin conceptions are estimated to be 12% of all natural conceptions, of which only about 2% survive to term as twins and about 12% result in single births (36)].