M2 PHARMA-November 14, 2014-Natera's Panorama prenatal screening test identifies vanishing twins, tripology, study shows
Previous publications have demonstrated a clear clinical need showing that unidentified vanishing twins caused a substantial proportion (up to 15%) of false positive NIPT results, Gross explained.
The Panorama test offers a solution to this problem by leveraging a unique SNP-based technology (single-nucleotide polymorphisms) to recognise the presence of additional DNA signatures, thereby eliminating the error rates associated with vanishing twins.
According to Natera, this is the first peer-reviewed publication detailing the clinical identification of vanishing twin and triploid cases by NIPT.
Consequences of vanishing twins in IVF/ICSI pregnancies.
6 (Table 1) had a vanishing twin identified by ultrasounds at the 6th WG.
2) and one with a vanishing twin (identified by ultrasound) (mother No.
14), (15) Singletons who survive vanishing twins
may also be more likely to have problems like those typically seen in multiples, including lower birth weight.
Since vanishing twins have been shown by other investigators to be detrimental to the surviving fetus, "our results are yet another argument for elective single embryo transfer," she said.
Her study included 1,432 singleton pregnancies, with or without vanishing twins.
18), and the incidence of vanishing twin was significantly higher in the bleeding group (8.
The phenomenon of vanishing male conceptuses may be compared with that of vanishing twins
, due to twins disappearing before they are clinically recognized [twin conceptions are estimated to be 12% of all natural conceptions, of which only about 2% survive to term as twins and about 12% result in single births (36)].