TRPV1

(redirected from Vanilloid receptor 1)

TRPV1

A gene on chromosome 17p13.2 that encodes a protein which is a receptor for capsaicin and the structurally related vanilloids, and is a non-selective cation channel structurally related to the TRP family of ion channels. The receptor is also activated by high temperatures, suggesting that it functions as a transducer of noxious chemical and painful thermal stimuli in vivo.
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The role of prostaglandins, vanilloid receptor 1, 5-hydroxytryptamine type 3, and kinin receptors is well established.
5) Many of these same triggers activate the transient receptor potential vanilloid receptor 1 (TRPV1), a cell surface receptor nerve fiber.
Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain.
The activation of the vanilloid receptor 1 by the endogenic ligand AEA leads to degeneration of dopaminergic neurons (Kim et al.
Vanilloid receptor 1 expression in the rat urinary tract.
The vanilloid receptor 1 (VR1) is highly localized on nociceptive neurons and their peripheral and central processes (89).
Change of vanilloid receptor 1 following neuromodulation in rats with spinal cord injury.
Known receptors include the capsaicin-sensitive vanilloid receptor 1 (TRPV1) (Caterina et al.
Local inflammation increases vanilloid receptor 1 expression within distinct subgroups of DRG neurons.
The protein, vanilloid receptor 1 (VR1), sits on nerve cells.
Rationale for vanilloid receptor 1 antagonist-based therapies in asthma