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(vuh-lare-ee-en) ,


(trade name),


(trade name),


(trade name),


(trade name),

Belgium Valerian

(trade name),

Common Valerian

(trade name),

Fragrant Valerian

(trade name),

Garden Heliotrope

(trade name),

Garden Valerian

(trade name),

Indian Valerian

(trade name),

Mexican Valerian

(trade name),

Pacific Valerian

(trade name),


(trade name),


(trade name),

Valeriana officinalis

(trade name),

Valerianae radix

(trade name),

Valeriana rhizome

(trade name),


(trade name)


Therapeutic: antianxiety agents


May increase concentrations of the inhibitory CNS transmitter GABA.

Therapeutic effects

Improvement in sleep quality.


Absorption: Unknown.
Distribution: Unknown.
Metabolism and Excretion: Unknown.
Half-life: Unknown.

Time/action profile

PO30–60 min2 hrunknown


Contraindicated in: Pregnancy and lactation.
Use Cautiously in: Alcohol use (may have additive sedative effects); Surgery (discontinue use 2 weeks prior to elective procedures).

Adverse Reactions/Side Effects

Central nervous system

  • drowsiness
  • headache


  • dry mouth


  • Benzodiazepine-like withdrawal symptoms with discontinuation after long-term use


Additive CNS depression with alcohol, antihistamines, anesthetic agentssedative hypnotics and other CNS depressants.Alcohol-containing preparations may interact with disulfiram and metronidazole.Additive sedative effects can occur when used with herbal supplements with sedative properties such as kava, l-tryptophan, melatonin, SAMe, and St. John's wort.
Oral (Adults) Tea—1 cup tea 1–5 times daily. Tea is made by steeping 2–3 g root in 150 mL boiling water for 5–10 min then straining. Tincture—1–3 mL 1–5 times daily. Extract—400–900 mg up to 2 hours before bedtime or 300–450 mg divided tid.


Capsules: OTC
Extract: OTC
Tea: OTC
Tincture: OTC

Nursing implications

Nursing assessment

  • Assess degree of anxiety and level of sedation prior to and periodically throughout therapy.
  • Assess sleep patterns.
  • Assess response in the elderly population where drowsiness and loss of balance may pose a significant risk for injury.

Potential Nursing Diagnoses

Anxiety (Indications)
Risk for injury (Side Effects)


  • Take one to two hours before bedtime if used for nighttime hypnotic.
  • Administer orally three to five times daily to control anxiety.

Patient/Family Teaching

  • Encourage patients to avoid stimulants such as caffeine and to provide an environment that promotes restful sleep.
  • May cause drowsiness. Caution patient to avoid driving or other activities requiring alertness until response to drug is known.
  • Caution patient to avoid use of alcohol and other medications or herbals that have a sedative effect; may increase drowsiness.
  • Advise patients to discontinue 2 weeks prior to elective surgical procedures.
  • Inform patients not to take this herbal supplement if pregnant or breast-feeding.
  • Notify patients that dependence with withdrawal symptoms may develop with prolonged use.

Evaluation/Desired Outcomes

  • Decreased anxiety level.
  • Improvement in sleep with a feeling of restfulness without drowsiness upon awakening.
Drug Guide, © 2015 Farlex and Partners
References in periodicals archive ?
Genera Species Senecio 28 Calamagrostis 21 Nototriche 19 Poa 19 Gentianella 13 Valeriana 13 Werneria 10 Lupinus 9 Astragalus 9 Plantago 8 Festuca 8 Ranunculus 7 Mniodes 7 Pycnophyllum 6 Bartsia 6 Perezia 6 Geranium 6 Oxalis 6 Lachemilla 6 Xenophyllum 6 Cerastium 5 Hypochaeris 5 Sisyrinchium 5 Viola 5 Table 4.
Probably, presence of citric acid had influenced this qualitative parameter: so the treatment with citric acid (T2) is more suggested to improve Valeriana leaves' antioxidant capacity.
The rhizome and root extracts of Valeriana wallichii DC in various solvents were investigated for its antimicrobial effect.
The choice of these two varieties was justified by the fact that Valeriana officinalis is a species with different morphological characteristics, which involves differences not only in anatomy but also in accumulation of active substances.
Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial.
Valeriana jatamansi Rhizoma et Radix was purchased from a commercial source in Yunnan province, China.
Table 2: The effect of low frequency electromagnetic fields on seedlings growth, fresh and dry weight in Valeriana officinalis L.
En la presente contribucion se seleccionaron para su estudio cinco de las principales especies con raices y rizomas de uso medicinal y medicinal-comestible de la Patagonia: Valeriana clarionifolia, V.