Valeriana


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valerian

(vuh-lare-ee-en) ,

Amantilla

(trade name),

All-Heal

(trade name),

Baldrian

(trade name),

Baldrianwurzel

(trade name),

Belgium Valerian

(trade name),

Common Valerian

(trade name),

Fragrant Valerian

(trade name),

Garden Heliotrope

(trade name),

Garden Valerian

(trade name),

Indian Valerian

(trade name),

Mexican Valerian

(trade name),

Pacific Valerian

(trade name),

Tagara

(trade name),

Valeriana

(trade name),

Valeriana officinalis

(trade name),

Valerianae radix

(trade name),

Valeriana rhizome

(trade name),

Valeriane

(trade name)

Classification

Therapeutic: antianxiety agents
InsomniaAnxiety

Action

May increase concentrations of the inhibitory CNS transmitter GABA.

Therapeutic effects

Improvement in sleep quality.

Pharmacokinetics

Absorption: Unknown.
Distribution: Unknown.
Metabolism and Excretion: Unknown.
Half-life: Unknown.

Time/action profile

ROUTEONSETPEAKDURATION
PO30–60 min2 hrunknown

Contraindications/Precautions

Contraindicated in: Pregnancy and lactation.
Use Cautiously in: Alcohol use (may have additive sedative effects); Surgery (discontinue use 2 weeks prior to elective procedures).

Adverse Reactions/Side Effects

Central nervous system

  • drowsiness
  • headache

Gastrointestinal

  • dry mouth

Miscellaneous

  • Benzodiazepine-like withdrawal symptoms with discontinuation after long-term use

Interactions

Additive CNS depression with alcohol, antihistamines, anesthetic agentssedative hypnotics and other CNS depressants.Alcohol-containing preparations may interact with disulfiram and metronidazole.Additive sedative effects can occur when used with herbal supplements with sedative properties such as kava, l-tryptophan, melatonin, SAMe, and St. John's wort.
Oral (Adults) Tea—1 cup tea 1–5 times daily. Tea is made by steeping 2–3 g root in 150 mL boiling water for 5–10 min then straining. Tincture—1–3 mL 1–5 times daily. Extract—400–900 mg up to 2 hours before bedtime or 300–450 mg divided tid.

Availability

Capsules: OTC
Extract: OTC
Tea: OTC
Tincture: OTC

Nursing implications

Nursing assessment

  • Assess degree of anxiety and level of sedation prior to and periodically throughout therapy.
  • Assess sleep patterns.
  • Assess response in the elderly population where drowsiness and loss of balance may pose a significant risk for injury.

Potential Nursing Diagnoses

Anxiety (Indications)
Risk for injury (Side Effects)

Implementation

  • Take one to two hours before bedtime if used for nighttime hypnotic.
  • Administer orally three to five times daily to control anxiety.

Patient/Family Teaching

  • Encourage patients to avoid stimulants such as caffeine and to provide an environment that promotes restful sleep.
  • May cause drowsiness. Caution patient to avoid driving or other activities requiring alertness until response to drug is known.
  • Caution patient to avoid use of alcohol and other medications or herbals that have a sedative effect; may increase drowsiness.
  • Advise patients to discontinue 2 weeks prior to elective surgical procedures.
  • Inform patients not to take this herbal supplement if pregnant or breast-feeding.
  • Notify patients that dependence with withdrawal symptoms may develop with prolonged use.

Evaluation/Desired Outcomes

  • Decreased anxiety level.
  • Improvement in sleep with a feeling of restfulness without drowsiness upon awakening.

Valeriana

a genus of herbaceous plants providing second class forage for livestock. Has a fleshy root containing valeric acid. V. officinalis is used for extraction of commercial valeric acid.
References in periodicals archive ?
Antispasmodic effects of Valeriana compounts: An in-vivo and in-vitro study on the guinea-pig ileum," Arch Int Pharma, 257: 274, 1982.
Matricaria recutita and Valeriana officinalis are indicated in this category.
Altogether, the literature data are in accordance with a lack of genotoxic properties of preparations of Valeriana officinalis L.
The MAP stage 1 was initiated using pantethine 500 mg and choline bitartrate 2000 mg along with B complex twice daily, a botanical formula (two parts each Passiflora incarnata and Crataegus oxycantha, one part each of Valeriana officinalis and Leonorus cardiaca), 2 mL three times/day, and magnesium glycinate 480 mg/day.
Other species-rich paramo taxa, such as Valeriana, Gentianella, and Lupinus, are equally fascinating examples of adaptive radiation in the northern Andes (von Hagen & Kadereit, 2001; Bell & Donoghue, 2005; Hughes & Eastwood, 2006).
Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress.
Oriel Chavez, 22, of Eugene, and Valeriana Cervantes, 23, of Springfield.
A FOR the irritability and tension, I would suggest that you take the remedy Zincum Valeriana at a dose of 15 drops, twice a day, before meals and this should be of some help to you.
Can Valeriana officinalis root extract prevent early postoperative cognitive dysfunction after CABG surgery?