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Valaciclovir. Valaciclovir has also been used with success in preventing CMV infection in KTR [111].
Aciclovir, valaciclovir and valganciclovir inhibit the enzyme responsible for copying viral DNA in an infected cell.
The firm also launched nine new products last year, including Valaciclovir and Imipenem + Cilastatin.
In the Sullivan et al study7 (which showed no benefit of adding aciclovir to steroids) the mean HouseBrackmann grade was 3.6, whereas the mean score was 4.3 in the Hato et al study, which reported a significant benefit of adding valaciclovir (97 versus 90 percent).21
standard-dose valaciclovir (500 mg daily), and those receiving standard- vs.
To assess whether standard and/or high doses of acidovir and valaciclovir affect these subclinical periods of HSV reactivation, they enrolled participants between November 2006 and July 2010 into the three studies, each with a 4- to 7-week initial treatment period, followed by a 1-week washout period, followed by crossover to the other treatment for an additional 4-7 weeks.
According to IMS Health, Valaciclovir had US sales of approximately USD1.5bn (EUR1.06m) for the 12 months ending 31 December 2010.
penciclovir, valaciclovir, famciclovir, and ganciclovir and others) have been approved for treatment of HSV-1 infections worldwide (Galasso et al., 1997; Leung and Sacks, 2000; Brady and Bernstein, 2004).
Rara vez requiere tratamiento, por ello, se aconseja, cuando al paciente le cause incomodidades o molestias de tipo estetico o funcional, administrar antifungicos para impedir la sobreinfeccion por Candida, y aciclovir y valaciclovir para evitar la reproduccion del virus y lograr la resolucion clinica de la leucoplasia.
The effect of valaciclovir on cytomegalovirus viremia and viruria detected by polymerase chain reaction in patients with advanced human immunodeficiency virus disease: AIDS ClinicalTrials Group Protocol 204/Glaxo Wellcome 123-014 International CMV Prophylaxis Study Group.