amprenavir(redirected from VX-478)
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an HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection; administered orally.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
amprenavirA protease inhibitor used with other antiretrovirals for managing HIV-1 (e.g., nelfinavir, indinavir or saquinavir).
Nausea, vomiting, diarrhoea, headache, perioral paraesthesias, gastric discomfort, rash, hyperglycaemia, diabetes, acute haemolytic anaemia, spontaneous bleeding in haemophiliacs, fat redistribution.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
amprenavirAIDS A protease inhibitor in clinical trials for treating HIV, used in combination with other protease inhibitors–eg, nelfinavir, indinavir, or saquinavir Adverse effects N&V, diarrhea, headache, perioral paresthesias, stomach discomfort, rash; other effects include hyperglycemia, DM, acute hemolytic anemia, spontaneous bleeding in hemophiliacs, and fat redistribution. See AIDS, Combination therapy, HIV, Protease inhibitor.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
amprenavirA protease inhibitor drug used to treat HIV infections. A brand name is Agenerase.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005