VX-478 | definition of VX-478 by Medical dictionary
amprenavir (redirected from VX-478)
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amprenavir A protease inhibitor used with other antiretrovirals for managing HIV-1 (e.g., nelfinavir, indinavir or saquinavir).
Nausea, vomiting, diarrhoea, headache, perioral paraesthesias, gastric discomfort, rash, hyperglycaemia, diabetes, acute haemolytic anaemia, spontaneous bleeding in haemophiliacs, fat redistribution.
amprenavir AIDS A protease inhibitor in clinical trials for treating HIV, used in combination with other protease inhibitors–eg, nelfinavir, indinavir, or saquinavir Adverse effects N&V, diarrhea, headache, perioral paresthesias, stomach discomfort, rash; other effects include hyperglycemia, DM, acute hemolytic anemia, spontaneous bleeding in hemophiliacs, and fat redistribution. See AIDS, Combination therapy, HIV, Protease inhibitor.
amprenavir A protease inhibitor drug used to treat HIV infections. A brand name is Agenerase.