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(vak-sin'e-a) [ vaccine + -ia],


A contagious disease of cattle, produced in humans by inoculation with cowpox virus to confer immunity against smallpox. Papules form about the third day after vaccination, changing to umbilicated vesicles about the fifth day, and at the end of the first week becoming umbilicated pustules surrounded by red areolae. They dry and form scabs, which fall off about the second week, leaving a white pitted depression. Synonym: cowpox; vaccina See: vaccination; varicella; variola

vaccinia necrosum

Spreading necrosis at the site of a smallpox vaccination; may be accompanied by similar necrotic areas elsewhere on the body.
Synonym: progressive vaccinia

progressive vaccinia

vaccinia necrosum.
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