TEK

(redirected from VMCM)
Also found in: Dictionary, Acronyms.

TEK

A gene on chromosome 9p21 that encodes a transmembrane tyrosine protein kinase that forms a heterodimer with TIE1, modulating its activity. TEK acts as a receptor for ANGPT1, ANGPT2 and ANGPT4, regulating angiogenesis; endothelial cell survival, proliferation, migration, adhesion and cell spreading; reorganisation of the actin cytoskeleton; and, depending on context, maintenance of vascular quiescence. TEK has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels into interstitial tissue. It is required for normal angiogenesis and heart development during embryogenesis, and it is required for postnatal haematopoiesis.
References in periodicals archive ?
a strategic advisory firm on business and technology, recently evaluated VMCM in its March 2002 report titled "The Portal Framework: The New Battle for the Enterprise Desktop" and concluded the following:
Vignette enhanced VMCM to increase the impact of content management on a company's bottom line, while also increasing the ease of use for those employees charged with managing the information their company delivers via their Web sites and portals," said Dave Shirk, senior vice president of products at Vignette.
By deploying VMCM within a Sun environment, customers now can tightly integrate Vignette's best-of-breed content management functionality within Sun's industry-standard portal infrastructure," said Dave Shirk, senior vice president of products at Vignette.
Further, by leveraging the powerful content management capabilities in Vignette V6, VMCM is able to integrate legacy content into sites and portals, providing a uniquely relevant and personalized experience for each visitor.
More information about the VMCM and Vignette's other content management applications can be found by visiting http://www.