VCAM-1


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VCAM-1

Vascular cell adhesion molecule 1. A cell-surface sialoglycoprotein encoded by VCAM1 on 1p32-p31, which belongs to the Ig superfamily, is expressed by cytokine-activated endothelium, and is involved in early inflammation. It mediates leukocyte-endothelial cell adhesion and signals transduction, recruiting monocytes and lymphocytes to the endothelial cell surface, triggering a chronic inflammatory response linked to atherosclerosis and rheumatoid arthritis.

vascular cell adhesion molecule-1

,

VCAM-1

A cell adhesion molecule that helps bind white blood cells such as lymphocytes or monocytes to the endothelium of blood vessels.
Synonym: vascular cell adhesion protein
References in periodicals archive ?
A natural log transformation [ln(X)] was applied to the following variables to normalize their distributions: uAs, toenail As, BMI, VCAM-1, ICAM-1, MMP-9, TNF-[alpha], PAI-1, and 15-[F.
Average CT values for VCAM-1, VEGFR-2, eNOS, and MMP-9 were calculated and normalized to that for [sz]-actin, and the normalized values were subjected to a 2−?
Gene expression of TNF-[alpha] (A), MCP-1 (B), IL-18 (C), VCAM-1 (D), IL-10 (E), IL-1b (F), MMP-9 (G), MMP-12 (H), LDLR (I), LRP-1 (J), CD-36 (K), in control native and grafted hearts, and LDE-MTX grafted hearts of the rabbits.
It has been determined that patients with elevated plasma VCAM-1 concentration and stable coronary heart disease are at higher risk of future cardiovascular events.
The aim of the present study is to search the association of ICAM-1, VCAM-1, Cyclin D1 and Cathepsin D immunohistochemically with clinicopathological parameters in the patients diagnosed with invasive ductal breast carcinoma.
2]-microglobulin * TNF-[alpha] (a) * SAA Markers of endothelial * VCAM-1 cells/leukocyte activation * ICAM-1 and chemokines * P-selectin * MCP-1 * CD40 Ligand * MPO Markers of the * VWF thrombosis cascade * tPA * D-dimer * tPA antigen * PAI antigen * VWF:ADAMTS13 ratio * Fibrinogen Lipids, apolipoproteins, * [Lp-PLA.
Standardized curcuminoid extract (SCE) has the ability to protect HUVECs from vascular inflammation by suppressing LPS-induced expression of NF-[kappa]B, toll like receptor-4 (TLR-4), I CAM-1 and VCAM-1 (Angel-Morales et al.
If caveolin-1 is reduced, we see reduced levels of proatherogenic VCAM-1.
Similar to serum inflammatory markers, markers of endothelial dysfunction were also increased at the end of the study compared to the start of the study among the control group; however, among the intervention group, the serum levels of p-selectin and VCAM-1 were decreased, though not significantly, and the serum level of ICAM-1 was significantly decreased at the end of the study.
Cytofluorimetric analysis of adhesion molecule surface expression showed a significant reduction of TNF-[alpha]-induced ICAM-1 and VCAM-1 surface expression evaluated as MFI in response to both DHZ and DHZ dimer (Figures 3(a) and 3(b)).
04), in contrast the differences in serum levels of VCAM-1 and PAI-1 were not statistically significant.
En celulas endoteliales la TNSF14 induce una respuesta inflamatoria por regulacion positiva de la produccion de IL-8, VCAM-1 e ICAM-1, lo que favorece la disfuncion endotelial, la vasooclusion y las trombosis (26, 27).