Diagnosed with VACTERL association
at a young age, she has been served by Ronald McDonald House Charities throughout her life, particularly in Cincinnati, Ohio.
Therefore, abnormal notochord formation may lead to wide range of anomalies involving upper GI tract, respiratory tract, abdominal viscera, vertebra, and spinal cord as seen in VACTERL association
, OEIS (omphalocele, exstrophy, imperforate anus, and spinal deformities), and the Klippel-Feil syndrome .
The familial cases, so far reported are two cases of diabetic mothers that had children with Sirenomelia and Caudal dysgenesis and VACTERL association
35 Thumb agenesis accompanies Holt-Oram syndrome (OMIM-142900) VACTERL association
(OMIM-192350) phocomelia Seckel syndrome (OMIM-210600) thrombocytopenia-absent radius syndrome(OMIM-274000) Fanconi anemia (OMIM-227650)and Duane-radial ray syndrome (OMIM-607323).
Analysis of component findings in 79 patients diagnosed with VACTERL association
The combination of all the clinico-radiographic findings made VACTERL association
(VA) (Vertebral anomalies, Anal atresia, Cardiac defects, Tracheoesophageal fistula and/or Esophageal atresia, Renal anomalies and Limb defects) the most likely diagnosis.
My six-year-old daughter, Chantel, was diagnosed with kidney problems, deaf in one ear, blindness as a result of immature retinas (though that has corrected itself), and spinal cord anomalies problems, and VACTERL association
(Vertebral anomalies, Anal Atresia, congenital Cardiac disease, Tracheo Esophageal fistula, Renal anomalies, radial dysplasia, and other Limb defects).
INTRODUCTION: VACTERL association
is a mnemonically useful acronym for a condition characterized by sporadic, non-random association of specific birth defects of multiple organ system, described in early 1970.
We would like to clarify that the term Vater sequence is currently not appropriate and it has been replaced by the term VACTERL association
from the acronym vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal malformations, and limb defects (4).
Mandy, who will be entering the second grade in the fall was born with VACTERL Association
Mandy's condition, VACTERL association
, involved a number of medical problems, including kidney and spinal defects, but I was so concerned with Mandy's arms that her other conditions seemed to pale in comparison.
Sirenomelia and VACTERL association
in the offspring of a woman with diabetes.