ocular melanoma

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ocular melanoma

Melanoma of choroid Oncology A melanoma linked to sun exposure affecting Pts with light skin and blue eyes Clinical Asymptomatic early; eventually causes retinal detachment and vision distortion. See Melanoma.

Ocular melanoma

A malignant tumor that arises within the structures of the eye. It is the most common eye tumor in adults.
Mentioned in: Eye Cancer
References in periodicals archive ?
Uveal melanoma is a rare and aggressive form of melanoma, which affects the eye, typically has a poor prognosis and for which there is no currently accepted optimal management or treatment.
Role of epigenetics in uveal melanoma. Int J Biol Sci 2017;13:426-33.
Uveal Melanoma. A tumor response was observed in 4 patients (3.6%; 95% CI: 1.0-9.0%) treated with chemotherapy (including 2 patients with complete response and 2 patients with partial response) and in no patient treated with immunotherapy (0%; 95% CI: 0.0-3.6%).
Solovieva et al., "Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in uveal melanoma and Fanconi anaemia," Oncogene, vol.
Brady, "Enucleation after plague radiotherapy for posterior uveal melanoma: histopathologic findings," Ophthalmology, vol.
Our patient with this metastatic uveal melanoma with extensive liver metastases with GNQ-209P mutation on the tissue biopsy (Figures 3 and 4) and undetectable mutations on the peripheral blood molecular profiling in serial follow-up samples suggests marked response to nabpaclitaxel.
Dr Christina Coughlin, chief medical officer at Immunocore, commented on the data: "We are excited to share these data in advanced uveal melanoma at ASCO.
Uveal melanoma is the most common malignant intraocular tumor in adults, which accounts for 3.7% of all melanoma cases.
Murali, "BAP1 protein loss by immunohistochemistry: a potentially useful tool for prognostic prediction in patients with uveal melanoma," Pathology, vol.
Servois et al., "Pyrophosphorolysis-activated polymerization detects circulating tumor DNA in metastatic uveal melanoma," Clinical Cancer Research, vol.
Uveal melanoma is the most common primary intraocular malignancy in adults.