usual interstitial pneumonia


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usual interstitial pneumonia

Pulmonology A condition of middle-aged individuals, often associated with connective tissue disease, characterized by insidious deterioration of respiratory function with dyspnea, tachypnea, right-sided heart failure, ↓ lung capacity, ↓ residual volume Imaging Early, 'ground-glass', linear or nodular markings, followed by coarsened shadows and cyst formation; diaphragmatic elevation in end-stage UIP reflects tissue loss Management None effective, possibly corticosteroids
References in periodicals archive ?
Usual interstitial pneumonia in rheumatoid arthritis-associated interstitial lung disease.
The 2011 official American Thoracic Society and European Respiratory Society (ATS/ERS) statement on the diagnosis and treatment of idiopathic pulmonary fibrosis (IPF), among other recommendations, recognized that a histopathologic confirmation was not needed in patients with idiopathic ILD who had a usual interstitial pneumonia (UIP) pattern on HRCT of the chest.
The 190-gene Envisia classifier detects the genomic pattern of usual interstitial pneumonia, a hallmark of IPF, with high accuracy (88% specificity and 70% sensitivity).
A HRCT scan was performed, and all the three IPF patients were consistent with a definitive usual interstitial pneumonia (UIP) pattern on HRCT (which is updated as 'typical UIP' according to the Fleischner Society White Paper[11]), including the presence of bilateral, predominantly subpleural, basal reticular abnormalities, traction bronchiectasis, and honeycombing and the absence of additional features considered incompatible with a diagnosis of IPF.
[1,2] The pathological correlate is usual interstitial pneumonia (UIP).
Xu et al., "Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparison of the clinicopathologic features and prognosis," Journal of Thoracic Disease, vol.
Ferrans, "Idiopathic nonspecific interstitial pneumonia: prognostic significance of cellular and fibrosing patterns: survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia," The American Journal of Surgical Pathology, vol.
PLCH shares it cystic pathogenesis with usual interstitial pneumonia which is distinguished by clustered distribution of its cysts preponderant in the lower lung zones [14].
If the high resolution CT (HRCT) scan is typical for a usual interstitial pneumonia (UIP), no biopsy of any kind is indicated to confirm a UIP pattern [2].
Baga et al., "Nonspecific interstitial pneumonia and usual interstitial pneumonia with mutation in surfactant protein C in familial pulmonary fibrosis," Modern Pathology: An Official Journal of The United States And Canadian Academy of Pathology, vol.
High-resolution computed tomography features of nonspecific interstitial pneumonia and usual interstitial pneumonia. J Comput Assist Tomogr.
IPF is characterized by variable degrees of inflammation and scarring and is associated with a histologic or radiologic pattern of usual interstitial pneumonia (UIP).