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Related to Uremic toxins: uremic syndrome


Relating to uremia.
Farlex Partner Medical Dictionary © Farlex 2012


(u-re'me-a) [ uro- + -emia]
Intoxication caused by the body's accumulation of metabolic by-products normally excreted by healthy kidneys. See: azotemia; uremic comauremic ('mik), adjective


Although nitrogen-containing waste products have long been considered the principal cause of uremia, other metabolic waste products (such as glycosylated wastes and byproducts of abnormal oxidation) may actually be the most important toxins responsible for uremia.


Symptoms include nausea, vomiting, anorexia, headache, dizziness, coma, or convulsions.


Dialysis removes many soluble waste products that accumulate in renal failure and helps improve some conditions associated with uremia. Other uremic conditions can be alleviated with a protein-restricted diet, careful management of acid-base balance, and calcium and folate supplementation.

extrarenal uremia

Prerenal uremia.

prerenal uremia

Uremia resulting not from primary renal disease but from such conditions as disturbances in circulation, fluid balance, or metabolism arising in other parts of the body. Synonym: extrarenal uremia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Many uremic toxins, already elevated in patients with less advanced cases, often go under the radar without astute laboratory exploration.
Uremic toxins are considered to be a new type of cardiovascular risk factor in CRD patients.
Brunet, "Vascular incompetence in dialysis patients-protein-bound uremic toxins and endothelial dysfunction," Seminars in Dialysis, vol.
Scatena et al., "Long term variation of serum levels of uremic toxins in patients treated by post-dilution high volume on-line hemodiafiltration in comparison to standard low-flux bicarbonate dialysis: results from the REDERT study," Journal of Nephrology, vol.
Additional benefits in reducing the burden of uremic toxins, generated both by microbiota and CKD condition, were noticed under a vegetarian diet; however, increasing attention must be paid in regard to serum potassium levels [62,63].
In addition, low concentrations of the uremic toxin methylglyoxal were shown to increase the NQO1 mRNA concentration [28].
Fukagawa, "Accumulated uremic toxins attenuate bone mechanical properties in rats with chronic kidney disease," Bone, vol.
This time, the scientific rationale behind the diet is more robust, with our evolving understanding of protein as a precursor for key nephrovascular uremic toxins (Mafra, Barros, & Fouque, 2013).
Hemodialysis is the only method of removing uremic toxins and therapy for the end stage renal disease patients.
It can be due to uraemia-related abnormalities particularly involving calcium phosphorus and parathyroid hormone metabolism accumulation of uremic toxins systemic inflammation cutaneous xerosis and common co-morbidities such as diabetes mellitus and viral hepatitis.