up-regulation

up-regulation

 [up reg-u-la´shun]
increase in expression of a gene; in the narrowest sense, that in which transcription of a specific mRNA is increased, but also used more broadly to refer to increase in mRNA levels for a particular gene from any cause, such as increased stability of the specific mRNA.

up-regulation

/up-reg·u·la·tion/ (up reg-u-la´shun) increase in expression of a gene; most narrowly, that due to increased transcription of a specific mRNA, but also used more broadly for increase in mRNA levels for the gene by any means.

up-regulation

[up reg-u-la′shun]
increase in expression of a gene; in the narrowest sense, that in which transcription of a specific mRNA is increased, but also used more broadly to refer to an increase in mRNA levels for a particular gene from any cause, such as increased stability of the specific mRNA. See also down-regulation.
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References in periodicals archive ?
Contract notice: maintenance, repair and up-regulation services for the lifting devices at paris 13 university
Shorter patient survival was generally associated with up-regulation of genes involved in mitosis and cell growth, and down-regulation of genes involved in cellular differentiation.
It is under research that expression of RNA binding protein human antigen R (HuR) in breast cancer causes up-regulation of cyclin E1 but other researches show miR-16 represses cyclin E1.
Here, we found that 40% of the mammary tumors showed up-regulation of COX-2 gene with fold changes i.
After LPS stimulation, the mRNA expression of toll-like receptor 4, myeloid differentiation factor 88, and TNF-a in both mice kidneys and HK-2 cells were all up-regulated, while RvD1 substantially inhibited the up-regulation of these genes.
For example, they demonstrated up-regulation of PLFN2, a protein that covers lipid droplets.
For example, they demonstrated up-regulation of PLIN2, a protein that covers lipid droplets.
Up-regulation of proPO and [alpha]-2-M was detected in hemocytes of NHP-B-infected shrimp before the use of antibiotics (Fig.
GBE showed up-regulation for hepatic IRS-1 and down-regulation for PEPCK, however, up-regulation for GLUT-4 and PPAR-a found in muscle.
In addition, pro-caspase-3 and 8 protein expression were up-regulated despite normalized GAPDH expression between samples, which may be related to the transcriptional up-regulation (Fig.
In animal studies we have found an up-regulation of adipogenic and lipogenic transcription factors in intrauterine growth restricted offspring as well as in offspring of obese mothers (Reprod Sci.