stem cell

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stem cell

1. any precursor cell;
2. a cell with daughter cells that may differentiate into other cell types.
3. a cell capable of maintaining its own number while exporting progeny to one or more cell lineages.

stem cell

n.
An unspecialized cell that can give rise to one or more different types of specialized cells, such as blood cells and nerve cells. Stem cells are present in embryos and in various tissues of adult organisms and are widely used in scientific research.

stem cell

(stem sel)
1. Any precursor cell.
2. A cell with daughter cells that may differentiate into other cell types.

stem cell

a special kind of cell from an EMBRYO, FOETUS or adult, capable of renewing itself under certain conditions, and of becoming specialized cells that make up the different TISSUES and ORGANS of the body A stem cell remains largely undifferentiated and uncommitted to a specific function, until it receives a signal to develop into a specialized cell (see CELL DIFFERENTIATION). An embryonic stem cell derives from a group of cells, the inner cell mass, from a 4–5 day old embryo, called a BLASTOCYST. This group of cells can be removed and cultured into embryonic stem cells. An embryonic germ cell derives from foetal cells destined to be reproductive cells (see GERM LINE). Embryonic stem cells and germ cells have the potential to differentiate into almost any or all of the cell types of the body i.e. they are ‘pluripotent’, but they do not have identical properties. An adult stem cell is an undifferentiated cell occurring in differentiated tissue, such as that of BONE MARROW, BRAIN, SKELETAL MUSCLE, LIVER, SKIN, PANCREAS or the BLOOD, with the capacity to yield specialized cell types of the tissue of origin. However, adult stem cells appear to have the potential to generate specialized cells of another tissue under appropriate conditions, for example cells from bone marrow generating cells resembling NEURONS and other cell types found in the brain. Hence it seems that they are capable of being genetically reprogrammed. The ability of stem cells to proliferate and to differentiate into specialized cell types makes them potentially useful for the repair and replacement of damaged and diseased tissues, see THERAPEUTIC CLONING.

Stem cell

Undifferentiated cell that retains the ability to develop into any one of numerous cell types.

stem cell

(stem sel)
1. Any precursor cell.
2. Cell with daughter cells that may differentiate into other cell types.
References in periodicals archive ?
Donehower and his colleagues speculate that the conditions seen in the mutant mice result from a p53-mediated reduction in the ability of unspecialized cells to proliferate and keep tissues healthy.
Stem cells are versatile, unspecialized cells that can reproduce themselves and also produce more specialized cells needed by the body.
Stems cells are basic, unspecialized cells that serve as the point of departure for the differentiated cells making up muscle, neural, blood and germinal tissues.
These are fast-growing, unspecialized cells that may be able to produce a wide variety of cells and tissues needed by the body.
In the past, they identified the eye's reservoir of unspecialized cells, so-called stem cells, that replenish corneal tissue.
Stem cells are fast-growing, unspecialized cells that can reproduce themselves, and also produce more specialized cells as needed.
The unspecialized cells that normally give rise to the various cell types in the brain can also act as bone marrow, the crucial source of an adult body's blood cells.
The NIH guidelines authorize federal grants for researchers who want to kill human embryos to obtain their "pluripotent stem cells." These are very versatile and unspecialized cells that may someday be used for transplants to generate all the different kinds of cells and tissues in the human body.