USP4

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USP4

A gene on chromosome 3p21.3 that encodes an enzyme which deubiquitinates target proteins (e.g., ADORA2A, PDPK1 and TRIM21), increasing the amount of functional receptors at the cell surface. USP4 plays a role in regulating quality control in the endoplasmic reticulum; it interacts with RB1, RBL1 and RBL2 and is expressed in the hippocampus.
 
Molecular pathology
USP4 is overexpressed in small cell carcinomas and adenocarcinomas of the lung.
References in periodicals archive ?
Its stock is traded on Nasdaq National Market under the symbol UNPH and its shares are included in the Nasdaq-100 index.
UIS Unisys Corporation UNPH Uniphase Corporation VRTS VERITAS Software VTSS Vitesse Semiconductor XLNX Xilinx, Inc.
UNPH Uniphase Corporation UIS Unisys Corporation VRTS VERITAS Software VTSS Vitesse Semiconductor XLNX Xilinx, Inc.
Its stock is traded on the Nasdaq National Market under the symbol UNPH and its shares are included int he Nasdaq-100 Index.
Uniphase's shares are quoted on Nasdaq National Market under the symbol UNPH.