denaturation

(redirected from Undenatured)
Also found in: Encyclopedia.

denaturation

 [de-na″chur-a´shun]
a change in the usual nature of a substance, as by the addition of methanol or acetone to alcohol to render it unfit for drinking, or the change in the physical properties of a substance, such as a protein or nucleic acid, caused by heat or certain chemicals that alter tertiary structure.
protein denaturation any nonproteolytic change in the chemistry, composition, or structure of a native protein that causes it to lose some or all of its unique or specific characteristics.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

de·na·tur·a·tion

(dē-na'tyū-rā'shŭn),
The process of becoming denatured.
Farlex Partner Medical Dictionary © Farlex 2012

de·na·tur·a·tion

(dē-nā'chŭr-ā'shŭn)
The process of becoming denatured.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

denaturation

1. Alteration in the folding pattern of a protein by heat or chemical reaction from its physiological conformation to an inactive shape.
2. In the case of DNA or RNA the conversion from a double-stranded structure to a single stranded structure, usually by heating. This is an essential stage in the POLYMERASE CHAIN REACTION.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

denaturation

the breakdown of the bonds forming the quaternary, tertiary and secondary structures of PROTEINS and NUCLEIC ACIDS, a process that can be caused by various agents, such as excess heat, strong acids or alkalis, organic solvents and ultrasonic vibration. In some cases, denaturation is irreversible as in, for example, the heating of egg albumen to give solid egg white. When denaturation occurs in enzymes, they are inactivated, with major effects in living organisms. Denatured nucleic acids can often be returned to their original configuration in the process of renaturation.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
* 2009 forward: Calculated by EIA as the annual quantity-weighted average of the thermal conversion factors for undenatured ethanol (3.539 million Btu per barrel), natural gasoline used as denaturant (4.620 million Btu per barrel), and conventional motor gasoline and motor gasoline blending components used as denaturant (5.253 million Btu per barrel).
Fortunately, scientists have discovered a substance called undenatured type II collagen, or UC-II[R], that retrains killer T-cells (which destroy target cells) so that they recognize collagen as a harmless substance--preventing the joint damage seen in osteoarthritis.
Derived from chicken cartilage, undenatured type II collagen has robust data showing reduction in pain and increase in function in dogs, horses, and humans.
With the use of membrane technology, it is possible to concentrate and separate whey proteins in their undenatured form with high functional property in native whey as compared to traditional sweet cheese whey (Maubois, 2002).
Dietary ingredients subjected to human clinical trials that have shown potential in managing OA-associated symptoms include glucosamine, chondroitin sulfate, avocado soybean unsaponifiables (ASU), pycnogenol and collagen (in both undenatured and hydrolysed forms).
Four volumes of 100% undenatured ethanol were added into RPE buffer.
Isolation and characterization of undenatured chlorogenic acid free sunflower (Helianthus annuus) proteins.
Our study tested the effects of an undenatured whey protein supplement rich in glutathione on human patients with hearing loss.
If you want to stop the flab of aging muscles and increase your strength, you want undenatured whey from grass-fed cows from A2 milk.
The new study has shown that UC-II, a novel undenatured type II collagen derived from chicken sternum cartilage can decrease arthritis pain by 33 percent, compared to 14 percent in groups treated with convetional therapies.
The resulting products are homogeneous, free-flowing, semi-hygroscopic light cream-colored undenatured powders that are fully soluble across wide pH ranges.