remifentanil

(redirected from Ultiva)

analgesic

 [an″al-je´zik]
1. relieving pain.
2. pertaining to analgesia.
3. an agent that relieves pain without causing loss of consciousness.
narcotic analgesic opioid analgesic.
nonsteroidal antiinflammatory analgesic (NSAIA) nonsteroidal antiinflammatory drug.
opiate analgesic (opioid analgesic) any of a class of compounds that bind with a number of closely related specific receptors (opioid receptors) in the central nervous system to block the perception of pain or affect the emotional response to pain; such compounds include opium and its derivatives, as well as a number of synthetic compounds, and are used for moderate to severe pain. Chronic administration or abuse may lead to dependence.

remifentanil

/rem·i·fen·ta·nil/ (rem″ĭ-fen´tah-nil) an opioid analgesic used as the hydrochloride salt as an anesthesia adjunct.

remifentanil

an opiate agonist analgesic.
indications It is used in combination with other drugs in general anesthesia and as a primary anesthetic in general surgery.
contraindications Use is prohibited in people with hypersensitivity to remifentanil and in children less than 12 years of age.
adverse effects Life-threatening effects are asystole, respiratory depression, and apnea. Other adverse effects include drowsiness, confusion, sedation, euphoria, delirium, agitation, anxiety, anorexia, constipation, cramps, dry mouth, urinary retention, dysuria, rash, urticaria, bruising, flushing, diaphoresis, pruritus, tinnitus, blurred vision, miosis, diplopia, palpitations, change in blood pressure, facial flushing, syncope, and rigidity. Common side effects are dizziness, headache, nausea, vomiting, and bradycardia.

remifentanil

Ultiva® Anesthesiology An opioid anesthetic that is 250-fold more potent than morphine. See Opioid anesthetic. Cf Muscle relaxant.

remifentanil

A narcotic painkiller used during the induction or maintenance of general anaesthesia. The use of painkillers during general anaesthesia is not, as it may seem, pointless. Painful stimuli act on the autonomic nervous system causing effects that can interfere with the smooth conduct of the anaesthetic and the post-operative period. A brand name is Ultiva.

remifentanil

a fentanyl derivative; a μ agonist.
References in periodicals archive ?
The advisory committee made their recommendation to the FDA following a day-long review of data on Ultiva as well as discussion of the company's proposed labeling, including indications, and the company's educational plans for anesthesia practitioners.
Unlike the traditional opioids used in anesthesia, Ultiva undergoes organ independent elimination via non-specific esterases (enzymes) found throughout the body.
Glaxo Wellcome is pursuing indications for use of Ultiva as an analgesic agent during the induction and maintenance of general anesthesia for inpatient and outpatient procedures and for continuation as an analgesic under the direct supervision of an anesthesia practitioner in a postoperative anesthesia care unit or intensive care unit setting.
Efficacy data presented at the meeting demonstrated that Ultiva has a rapid onset, a rapid achievement of peak effect and an ultra short duration of action.
The flexibility with Ultiva resulted in fewer responses to intubation and surgical stress and enabled a rapid and predictable recovery," said Randal L.
More than 2,800 patients worldwide in 51 studies received Ultiva in the clinical trial program that established the drug's efficacy and safety profile.
Features fascinating case studies, including the discovery and development of erythromycin analogs, Tagamet, and Ultiva (remifentanil)
Sirgo, President and Chief Executive Officer of BDSI, commented, "Significant in Al's hiring was his oncology background and launch experience with Ultiva.