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Related to Uhthoff sign: Uhthoff's symptom
a transient temperature-dependent numbness, weakness, or loss of vision. Conduction stops in any nerve if the temperature becomes too elevated. In a damaged nerve, for example, by demyelinization, this shutdown temperature is lowered, and may approach normal body temperature. Transient neurologic dysfunction may then appear with a hot shower, exercise, or fever.
Synonym(s): Uhthoff syndrome
[Wilhelm Uhthoff, Ger. ophthalmologist, 1853–1927]
In patients with multiple sclerosis, the transient decrease in vision, double vision, or nystagmus when body temperature rises.