UCHL1

(redirected from Ubiquitin C-Terminal Hydrolase)
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UCHL1

A gene on chromosome 4p14 that encodes a ubiquitin-protein hydrolase, involved both in processing of ubiquitin precursors and ubiquitinated proteins, which recognises and hydrolyses a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds free monoubiquitin and may prevent its degradation in lysosomes.
References in periodicals archive ?
Shen, "The potential role of ubiquitin c-terminal hydrolases in oncogenesis," Biochimica et Biophysica Acta, vol.
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