USP47

USP47

A gene on chromosome 11p15.3 that encodes a deubiquitinase of the C19 peptidase family which acts on monoubiquitinated DNA polymerase beta (POLB), stabilising it and thereby playing a role in base-excision repair. USP47 regulates cell growth and genome integrity and may indirectly regulate CDC25A expression at a transcriptional level.
References in periodicals archive ?
Family Members USPL1, CYLD, USP1, USP2, USP3, USP4, USP5, USP6, USP7, USP YSP8, USP9x, USP10, USP11, USP12, USP13, USP14, USP15, USP16, USP17L2, USP18, USP19, USP20, USP21, USP22, USP23, USP24, USP25, USP26, USP27, USP28, USP29, USP30, USP31, USP32, USP33, USP34, USP35, USP36, USP37, USP38, USP39, USP40, USP41, USP42, USP43, USP44, USP45, USP46, USP47, USP48, USP49, USP50, USP51, USP52, USP53, USP54 OTUB1, OTUB2, OTUD1, OTUD3, OTUD4, OTUD5, OTUD6A, OTU OTUD6B, OTU1, HIN1L, A20, Cezanne, Cezanne2, TRABID, VCPIP1 UCH UCH-L1, UCH-L3, UCH37/UCH-L5, BAP1 Josephin ATXN3, ATXN3L, JOSD1, JOSD2 JAMM/MPN+ BRCC36, CSNS, POH1, AMSH, AMSH-LP, MPND, MYSM1, PRPF8 Table 2: Deubiquitinases and bone remodeling.
identified that ubiquit-inspecific peptidase 47 (USP47) and Ras-related protein Rab22A (RAB22A) were direct functional targets of miR-204-5p in GC and that miR-204-5p inhibited GC cell proliferation by downregulating USP47 and RAB22A [24].
Hu et al., "MicroRNA-204-5p inhibits gastric cancer cell proliferation by downregulating USP47 and RAB22A," Medical Oncology, vol.
USP47, RAB22A, SIRT1, Snai1, and so forth are targets of miR-204 that mediate miR-204 reducing the oncogenicity of gastric cancer [11, 22, 23].