USP3

USP3

A gene on chromosome 15q22.3 that encodes an enzyme which deubiquitinates monoubiquitinated target proteins, such as histones H2A and H2B. USP3 is required for progression through S-phase and mitotic entry; it may regulate the DNA damage response (DDR) checkpoint by deubiquitinating H2A at DNA damage sites. It associates with chromatin and is expressed in all tissues, especially the pancreas.
References in periodicals archive ?
synthetic absorbable polyfilament surgical suture material based on polyglycolide woven polyglycolide thread with coating, usp3 / 0, needle curvature , needle type-pricking, needle length-20mm ( 1), thread length 75-90 cm 264 pcs
Vissers et al., "Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells," The Journal of Experimental Medicine, vol.
To prevent its overactivation, RIG-I is actively targeted by many cellular factors that inhibit K63 ubiquitination (CYLD, USP1, and USP3) or tag it for proteasome degradation via K48 ubiquitin linkage (RNF122, RNF125) [19-23].
The DUBs that catalyze both H2A and H2B are USP3 and USP22.
Eugene Generals goaltender Christopher Alexakis has been named by the United States Premier Hockey League as the USP3's goaltender odf the week.
For example, a meta GWAS of incident heart failure (HF) identified a single HF-associated locus near the USP3 (3) (ubiquitin specific peptidase 3) gene (5).
Also in 2007,with help from the Federal Bureau of Investigation (FBI), FEBs nationwide were granted access to the Law Enforcement On-Line (www.leo.gov) and United States Public and Private Partnership (usp3.org) communications systems.
Public Private Partnership (USP3), an industry-funded nonprofit organization, plans to launch its own situational awareness Web- and message system based on HSIN CI and the FBI's Emergency Response Network (FBI ERN).
Dclre1a cerevisiae) BG069818 ubiquitin specific protease 3 Usp3 BG075881 tyrosine 3-monooxygenase/tryptophan Ywhaz 5-monooxygenase activation protein, zeta polypeptide GenBank Fold change (a) accession no.
synthetic resorbable poly-glycolide surgical suture based on polyglycolide polyethylene glycol filament with coating, usp3 / 0, needle curvature , needle-stitch type, needle length-20mm, thread length-75-90 cm 50 pcs.
Public-Private Partnership (called USP3), which is an information sharing initiative coordinated by the Department of Justice.
LOT 14 System petru microscope image acquisition and processing - 1pc; LOT 15: Optical Microscope - 5pcs; LOT 16: vid- pump 1pc; LOT 17: liofilizator- vacuum pump 1pc; LOT 18: distiller equipped with the filters 1pc; LOT 19: ultrapure water production system of water potabila- 1pc; LOT 20: Monodistilator glass support for wall mounting 1pc; LOT 21: Washing sticlarie- 1pc; LOT 22: Nest stirring heating - 1pc; LOT 23: termoreglabila- sand bath 1pc; LOT 24: Dissolution Apparatus Bio USP3 type Diss- 1pc; LOT 25: Bathroom 100 C 5pcs; LOT 26: recirculare- 1pc thermostat; LOT 27: Labo