USP20

USP20

A gene on chromosome 9q34.11 that encodes a deubiquitinating enzyme which regulates G protein-coupled receptor signalling by deubiquitinating the beta-2 adrenergic receptor (ADRB2), playing a central role in ADRB2 recycling and resensitisation after prolonged agonist stimulation. USP20 also deubiquitinates: DIO2, thereby regulating thyroid hormone; HIF1A, stabilising it and enhancing HIF1A-mediated activity; and both Lys-48- and Lys-63-linked polyubiquitin chains.
References in periodicals archive ?
Family Members USPL1, CYLD, USP1, USP2, USP3, USP4, USP5, USP6, USP7, USP YSP8, USP9x, USP10, USP11, USP12, USP13, USP14, USP15, USP16, USP17L2, USP18, USP19, USP20, USP21, USP22, USP23, USP24, USP25, USP26, USP27, USP28, USP29, USP30, USP31, USP32, USP33, USP34, USP35, USP36, USP37, USP38, USP39, USP40, USP41, USP42, USP43, USP44, USP45, USP46, USP47, USP48, USP49, USP50, USP51, USP52, USP53, USP54 OTUB1, OTUB2, OTUD1, OTUD3, OTUD4, OTUD5, OTUD6A, OTU OTUD6B, OTU1, HIN1L, A20, Cezanne, Cezanne2, TRABID, VCPIP1 UCH UCH-L1, UCH-L3, UCH37/UCH-L5, BAP1 Josephin ATXN3, ATXN3L, JOSD1, JOSD2 JAMM/MPN+ BRCC36, CSNS, POH1, AMSH, AMSH-LP, MPND, MYSM1, PRPF8 Table 2: Deubiquitinases and bone remodeling.
E possivel conhecer outros aspectos da personalidade de Pedreira de Freitas, recorrendo a depoimentos e registros de colegas e colaboradores em Passos (18), PAHO Foundation (19), IPTV USP20 e Esteto (21).