USP1 | definition of USP1 by Medical dictionary
Also found in: Acronyms
USP1 A gene on chromosome 1p31.3 that encodes a deubiquitinase which, upon interaction with WDR48, downregulates DNA damage repair effected by deubiquitination of monoubiquitinated FANCD2 and PCNA.
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References in periodicals archive
monitor series in-ear headphones will be available in a single finish - a black aluminum baffle mated to a hand-poured pewter housing.
Two nuclear localization signals in USP1
mediate nuclear import of the USP1/UAF1 complex.
In his letter Bliley wrote that the interpreter explained to the inspector that Hua Lian had "copied information from the Roussel NDA [the New Drug Application of Roussel Uclaf, the French company that first developed and manufactured RU486] in a number of sections rather than translate their own methods from Chinese to English." The inspector reported that the interpreter also relayed information that the firm's consultant "told them that FDA wants all raw materials to meet USP1
specifications so they inserted numerous references to general USP chapters in the CMC which have nothing to do with the testing they perform."