GPR98

(redirected from USH2C)

GPR98

A gene on chromosome 5q13 that encodes a G protein-coupled receptor highly expressed in the CNS and thought to have a key role in CNS development.

Molecular pathology
GPR98 mutations are associated with Usher syndrome 2 and familial febrile seizures.
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References in periodicals archive ?
PDZD7 has been shown to bind the three known USH2 proteins usherin (USH2A), ADGRV1 (USH2C), and whirlin (USH2D), forming the so-called ankle-link complex at the ankle region of hair cell stereocilia [17, 21-23].
Among the proteins identified, ADGRV1 (USH2C) is a known PDZD7-binding partner, whereas the interactions between PDZD7 and the other proteins have not been reported.