DPYSL2

(redirected from ULIP2)

DPYSL2

A gene on chromosome 8p22-p21 that encodes a member of the collapsin response mediator protein family, which forms homo- and heterotetramers. DPYSL2 plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration.  

Molecular pathology
DPYSL2 has been implicated in multiple neurological disorders; hyperphosphorylation of the encoded protein may play a role in the development of Alzheimer's disease.
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Among the 22 proteins, 11 were identified (Table 1); these were Ulip2 protein, tubulin beta chain 15, a actin, aldolase, M2 pyruvate kinase, panthenol-cytochrome C reductase core protein I, hydrolase at the end of ubiquitin carboxy, albumin, interleukin 1 receptor accessory protein, hemoglobin a chain, kappa-B motif-binding phosphoprotein, and calcium-binding protein.